Hepatitis C Virus (HCV)

CAS No.	Product Name	Inquiry
1613081-64-3	Ruzasvir
1613589-09-5	Adafosbuvir
1613589-24-4	EIDD-2749 4'-Fluorouridine is an orally active RdRp inhibitor. It effectively blocks the replication of RSV and SARS-CoV-2.
1621884-22-7	2'-Deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate sodium salt PSI-7409 tetrasodium is an active 5'-triphosphate metabolite of sofosbuvir (PSI-7977), inhibiting HCV NS5B polymerases, with IC50s of 1.6, 2.8, 0.7 and 2.6 μM for GT 1b_Con1, GT 2a_JFH1, GT 3a, and GT 4a NS5B polymerases, respectively.
1676100-30-3	Cyclophilin-inhibitor-3 Cyclophilin inhibitor 3 (compound 7c) is a potent cyclophilin A (CypA) inhibitor with an potent anti-HCV activity (EC50 of 4.2 M).
169516-60-3	6-Chloro-7-deazapurine-2F-β-D-arabinofuranose 4-Chloro-7-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine, known for its potent antiviral properties, is mainly used to study a wide array of viral infections such as HIV and hepatitis B. By impeding viral DNA replication, it effectively curtails the viral burden within the host organism.
1715934-43-2	MI 14 MI 14 is a PI 4-K IIIβ inhibitor with IC50 value of 54 nM. It shows antiviral activity against single-stranded positive sense RNA viruses in HeLa cell-based assays.
171674-89-8	Nitidanin Nitidanin is a natural compound isolated from the herbs of Zanthoxylum simulans Hance. (±)-Nitidanin is an antimalarial compound.
176652-07-6	Artemisinin-[d3] Artemisinin-[d3] is the labelled analogue of Artemisinin. Artemisinin is a natural product originally isolated from plants of the genus Artemisia. It effectively kills malarial parasites of the genus Plasmodium. It is usually used in combination therapy for the treatment of malaria. Artemisinin is also used against a wide range of trematodes, including Schistosoma.
1801709-41-0	Daclatasvir-d6 Daclatasvir-[d6], is the labelled analogue of Daclatasvir. Daclatasvir, inhibits the HCV protein NS5A, and can be used in combination with other medications to treat hepatitis C (HCV).
182959-28-0	YM-53601 free base YM-53601 free base is a squalene synthase inhibitor with an IC50 of 79 nM for human hepatoma cells. It is a lipid lowering agent that can reduce plasma cholesterol and triglyceride levels in vivo. It is also an inhibitor of farnesyl-diphosphate farnesyltransferase 1 (FDFT1) enzyme activity and can inhibit the proliferation of HCV.
182959-33-7	YM-53601 YM-53601 is a squalene synthase inhibitor with IC50s of 79 and 90 nM in HepG2 cells and rat liver microsomes, respectively. It is a lipid lowering agent that can reduce plasma cholesterol and triglyceride levels in vivo and inhibit cholesterol biosynthesis in rats (ED50 = 32 mg/kg). It is also an inhibitor of farnesyl-diphosphate farnesyltransferase 1 (FDFT1) enzyme activity and can inhibit the proliferation of HCV.
1850311-28-2	Hcv-IN-43
1850311-55-5	Hcv-IN-44
1868135-06-1	Sofosbuvir-[d6] Sofosbuvir-[d6] is the labelled analogue of Sofosbuvir. Sofosbuviis a medication used for the treatment of hepatitis C.
1903800-11-2	KIN1408 KIN1408 is an IRF3 activator with antiviral activity. It induces innate immune gene expression such as MDA5, RIG-1, Mx1, IRF7, and IFIT1 in THP-1 cells stimulated with phorbol 12-myristate 12-acetate (PMA).
1919828-83-3	DDX3-IN-1 DDX3-IN-1 is a DEAD-box polypeptide 3 (DDX3) inhibitor for HCV and HIV, respectively.
1929655-04-8	RG-101 RG-101 is a hepatocyte targeted N-acetylgalactosamine conjugated oligonucleotide that antagonises miR-122 . miR-122 is an important host factor for hepatitis C virus (HCV) replication.
1959593-23-7	Yimitasvir
1959593-63-5	Yimitasvir diphosphate

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