Hepatitis C Virus (HCV)

CAS No.	Product Name	Inquiry
1966138-53-3	Coblopasvir-dihydrochloride Coblopasvir (KW-136) dihydrochloride is a pangenotypic non-structural protein 5A (NS5A) inhibitor. Coblopasvir dihydrochloride can be used for research of chronic hepatitis C virus infection.
198821-22-6	Merimepodib Merimepodib is orally bioavailable IMPDH inhibitor.
19956-53-7	Lucidone Lucidone, coming from the root of Lindera strychnifolia, may possess antioxidant and anti-inflammatory properties and may be useful for the prevention of free radical-induced skin damage. The anti-inflammatory activity of lucidone might cause by the inhibition of iNOS and COX-2 expressions through the down-regulation of NF-κB and AP-1 binding activity. Besides, the effects of lucidone on tyrosinase and antimelanogenic activity were investigated, lucidone strongly inhibits the activity of mushroom tyrosinase. The antimelanogenic activity of lucidone is probably due to its inhibition of tyrosinase activity and the suppression of tyrosinase and MITF expression.
1998705-62-6	HCV-IN-31 HCV-IN-31 is an inhibitor of HCV, with an EC50/EC95 of 15.7 μM for HCV replicon.
1998705-64-8	Bemnifosbuvir Bemnifosbuvir is the precursor drug form of the antiviral nucleoside analogue AT-9010. It reduces the infectious virus yield in cells infected with Middle East respiratory syndrome coronavirus (MERS-CoV), severe acute respiratory syndrome CoV (SARS-CoV), SARS-CoV-2, human CoV 229E (HCoV-229E), and HCoV-OC43 (EC90s = 37, 0.47, 2.8, 1.2, and 0.5 µM, respectively).
200937-57-1	Fmoc-Leu-OH-[15N] Fmoc-Leu-OH-[15N] is a labelled L-Leucine-N-FMOC. Leucine is an α-amino acid essential for humans.
2050041-12-6	Ledipasvir-[d6] Ledipasvir-[d6] is the labelled form of Ledipasvir, which is intended for use as an internal standard for the quantification of ledipasvir by GC-or LC-MS.
2058080-25-2	HCV-IN-4 HCV-IN-4 is a potent and orally bioactive HCV NS5A inhibitor, displaying great potency against GT1a, GT2b, GT3a, GT1a Y93H and GT1a L31V, with EC90s values of 3 pM, 0.3 nM, 0.01 nM, 0.5 nM and 0.02 nM, respectively.
20724-73-6	2'-C-Methylcytidine A nucleoside analog with anti-hepatitis C virus (HCV) activity. Upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus viral replication.
20831-76-9	Gentiopicroside Gentiopicroside is isolated from the roots of Gentiana manshurica Kitag.
2087916-31-0	HCV-IN-39 HCV-IN-39 (Compound 18a) is a potent hepatitis C virus (HCV) nucleoside inhibitor with EC50 values of 0.644, 0.952 and 0.154 μM against GT1a, GT1b and GT1b CES1 replicons.
2087916-66-1	HCV-IN-40 HCV-IN-40 (Compound 18c) is a potent, orally active hepatitis C virus (HCV) nucleoside inhibitor with EC50 values of 0.259, 0.434 and 0.069 μM against GT1a, GT1b and GT1b CES1 replicons.
208939-95-1	Hepatitis-Virus-C-NS3-Protease-Inhibitor-2 Hepatitis Virus C NS3 Protease Inhibitor 2 is a product-based peptide inhibitor of hepatitis C virus (HCV) NS3 protease, with a Ki of 41 nM.
2095551-10-1	Sofosbuvir impurity M Sofosbuvir impurity M is a diastereoisomer and impurity of Sofosbuvir, an inhibitor of HCV RNA replication with strong anti-hepatitis C virus activity.
2128695-48-5	Ledipasvir hydrochloride
2140-72-9	2'-O-Methylcytidine Cytidine analog. Used for preparation of nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase.
2158336-69-5	Dasabuvir-d6 Dasabuvir-d6 (ABT-333-d6) is the deuterium labeled Dasabuvir. Dasabuvir (ABT-333) is a nonnucleoside inhibitor of the RNA-dependent RNA polymerase encoded by the HCV NS5B gene, inhibits recombinant NS5B polymerases derived from HCV genotype 1a and 1b clinical isolates, with IC50 between 2.2 and 10.7 nM.
2164516-85-0	Sofosbuvir impurity I Sofosbuvir impurity I is a diastereoisomer and impurity of Sofosbuvir, an inhibitor of HCV RNA replication with strong anti-hepatitis C virus activity.
2172676-02-5	Velpatasvir-[d7] Velpatasvir-[d7] is the labelled analogue of Velpatasvir, which is a selective Hepatitis C virus NS 5 protein inhibitor.
2189684-44-2	Lenacapavir Lenacapavir is a HIV-1 capsid inhibitor.

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