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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
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- Flavivirus
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- Hepatitis B Virus (HBV)
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- Human immunodeficiency Virus (HIV)
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- Rabies virus (RABV)
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- SARS-CoV
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- West Nile virus
- Antiviral intermediates
Zidovudine-d3
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| Category | Human immunodeficiency Virus (HIV) |
| Description | Zidovudine-d3 (Azidothymidine-d3) is the deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency. |
Product Information
| Synonyms | Azidothymidine-d3; AZT-d3; ZDV-d3 |
| Molecular Weight | 270.26 |
| Molecular Formula | C10H10D3N5O4 |
| Canonical SMILES | O=C(C(C([2H])([2H])[2H])=CN1[C@@H](C2)O[C@@H]([C@H]2N=[N+]=[N-])CO)NC1=O |
| Purity | ≥98% (HPLC) |
| Solubility | In vitro: 10 mM in DMSO |
| Appearance | Solid powder |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Complexity | 484 |
| Exact Mass | 270.11558415 |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and Metabolic profiles of drugs. |
| Target | HIV; CRISPR/Cas9 |
| XLogP3-AA | 0 |
