Z-Phe-Tyr(tBu)-diazomethylketone

Category	SARS-CoV
CAS	114014-15-2
Description	Z-Phe-Tyr(tBu)-diazomethylketone is an inhibitor of cathepsin L with selectivity for cathepsin L over cathepsin S and cathepsin B.

Quotation Now

Synonyms	Z-Phe-Tyr(tBu)-diazomethylketone;114014-15-2;Z-Phe-Tyr(OtertBut)-CHN..2..;Cathepsin L inhibitor III;86-03-3;benzyl N-[(2S)-1-[[(2S)-4-diazo-1-[4-[(2-methylpropan-2-yl)oxy]phenyl]-3-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate;Cathepsin L inhibitor III?;DTXSID60415510;Z-Phe-Tyr(t-Bu)-diazomethylketone;MFCD00672349;AKOS040754808;DA-51615;HY-138208;CS-0145953;benzyl ((S)-1-(((S)-1-(4-(tert-butoxy)phenyl)-4-diazo-3-oxobutan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate;Nalpha-[(benzyloxy)carbonyl]-N-[(2S)-1-(4-tert-butoxyphenyl)-4-diazo-3-oxobutan-2-yl]-L-phenylalaninamide;
IUPAC Name	benzyl N-[(2S)-1-[[(2S)-4-diazo-1-[4-[(2-methylpropan-2-yl)oxy]phenyl]-3-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Molecular Weight	542.63
Molecular Formula	C31H34N4O5
Canonical SMILES	O=C(N[C@H](C(C=[N+]=[N-])=O)CC(C=C1)=CC=C1OC(C)(C)C)[C@@H](NC(OCC2=CC=CC=C2)=O)CC3=CC=CC=C3
InChI	InChI=1S/C31H34N4O5/c1-31(2,3)40-25-16-14-23(15-17-25)18-26(28(36)20-33-32)34-29(37)27(19-22-10-6-4-7-11-22)35-30(38)39-21-24-12-8-5-9-13-24/h4-17,20,26-27H,18-19,21H2,1-3H3,(H,34,37)(H,35,38)/t26-,27-/m0/s1
InChIKey	CGONKNHDBTYOOC-SVBPBHIXSA-N
Purity	≥98%
Solubility	Soluble in ethyl acetate (10 mg/ml), and DMSO
Appearance	Solid
Storage	Store at -20°C