-
Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
XP-59
![{PARAM:[Name]}()](https://resource.bocsci.com/structure/890402-73-0.gif)
| Category | SARS-CoV |
| CAS | 890402-73-0 |
| Description | Benzotriazole esters have been reported as potent nonpeptidic inhibitors of the enzyme, XP-59 is a potent inhibitor of the SARS-CoV M(pro). |
Product Information
| Synonyms | XP 59 |
| IUPAC Name | benzotriazol-1-yl 4-(dimethylamino)benzoate |
| Molecular Weight | 282.3 |
| Molecular Formula | C15H14N4O2 |
| Canonical SMILES | CN(C)C1=CC=C(C=C1)C(=O)ON2C3=CC=CC=C3N=N2 |
| InChI | InChI=1S/C15H14N4O2/c1-18(2)12-9-7-11(8-10-12)15(20)21-19-14-6-4-3-5-13(14)16-17-19/h3-10H,1-2H3 |
| InChIKey | UOITWBIZHQLMTH-UHFFFAOYSA-N |
| Purity | 98% |
| Solubility | In vitro: 10 mM in DMSO |
| Appearance | Off-white to light yellow (Solid) |
| Storage | Store at 2-8°C |
| Complexity | 369 |
| Exact Mass | 282.11167570 |
| In Vitro | The SARS-CoV main proteinase (Mpro) plays a central role in the formation of the viral replicase/transcriptase complex and is thus an ideal target for the development of suitable drugs. |
| Target | Ki: 0.1 nM (SARS-CoV Mpro). |
| XLogP3-AA | 3.1 |
