-
Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
VP-14637
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| Category | Respiratory syncytial Virus (RSV) |
| CAS | 235106-62-4 |
| Description | VP-14637 is a small molecule inhibitor of respiratory syncytial virus (RSV) with EC50 value of 1.4 nM. It suppresses RSV via binding to the viral F protein and inhibiting the RSV fusion (EC50 = 5.4 nM). |
Product Information
| Synonyms | VP-14637;235106-62-4;MDT-637;2-[[2-hydroxy-5-[(5-methyltetrazol-1-yl)iminomethyl]phenyl]-(4-hydroxyphenyl)methyl]-4-[(5-methyltetrazol-1-yl)iminomethyl]phenol;HCW4G0O030;CID 135565536;UNII-HCW4G0O030;CHEMBL4297402;DTXSID10946228;MDT 637;2,2''-[(4-HYDROXYFENYL)METHYLEEN]BIS(4-{(E)-[(5-METHYL-1H-TETRAZOOL1-YL)IMINO]METHYL}FENOL);Q27279863;(4E)-2-[(4-hydroxyphenyl)-[(3E)-3-[[(5-methyltetrazol-1-yl)amino]methylidene]-6-oxocyclohexa-1,4-dien-1-yl]methyl]-4-[[(5-methyltetrazol-1-yl)amino]methylidene]cyclohexa-2,5-dien-1-one;2,2'-[(4-Hydroxyphenyl)methylene]bis(4-{[(5-methyl-1H-tetrazol-1-yl)amino]methylidene}cyclohexa-2,5-dien-1-one);2-((2-hydroxy-5-((E)-((5-methyl-1H-tetrazol-1-yl)imino)methyl)phenyl)(4-hydroxyphenyl)methyl)-4-((Z)-((5-methyl-1H-tetrazol-1-yl)imino)methyl)phenol; |
| IUPAC Name | 2-[[2-hydroxy-5-[(5-methyltetrazol-1-yl)iminomethyl]phenyl]-(4-hydroxyphenyl)methyl]-4-[(5-methyltetrazol-1-yl)iminomethyl]phenol |
| Molecular Weight | 468.6 |
| Molecular Formula | C29H40O5 |
| Canonical SMILES | C[C@H]1[C@@H]2CC(=O)C3=C([C@]2(CCC1=O)C)C(=O)C[C@]4([C@H]3CC[C@@H]4[C@H](C)CCC(=C)[C@H](C)C(=O)O)C |
| InChI | InChI=1S/C25H22N10O3/c1-15-28-30-32-34(15)26-13-17-3-9-23(37)21(11-17)25(19-5-7-20(36)8-6-19)22-12-18(4-10-24(22)38)14-27-35-16(2)29-31-33-35/h3-14,25,36-38H,1-2H3 |
| InChIKey | BLUJRJMLDHEMRX-UHFFFAOYSA-N |
| Melting Point | >225°C (dec.) |
| Purity | ≥98% |
| Appearance | Crystalline Solid |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
