-
Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
VCH-286
![{PARAM:[Name]}()](https://resource.bocsci.com/structure/891824-47-82d.gif)
| Category | Human immunodeficiency Virus (HIV) |
| CAS | 891824-47-8 |
| Description | VCH-286 is a C-C chemokine receptor 5 (CCR5) receptor antagonist, which can be used to treat HIV infection. |
Product Information
| Synonyms | 891824-47-8;NDX9EX5ATP;VCH-286;VCH286;4,4-Difluoro-N-((1S)-3-((1S,5R)-3'-isopropyl-2'-oxo-1'-(tetrahydropyran-4-ylmethyl)spiro(8-azabicyclo(3.2.1)octane-3,4'-imidazolidine)-8-yl)-1-phenyl-propyl)cyclohexanecarboxamide;Cyclohexanecarboxamide, 4,4-difluoro-N-((1S)-3-(3'-(1-methylethyl)-2'-oxo-1'-((tetrahydro-2H-pyran-4-yl)methyl)spiro((3-exo)-8-azabicyclo(3.2.1)octane-3,4'-imidazolidin)-8-yl)-1-phenylpropyl)-;UNII-NDX9EX5ATP;AKOS040749745;AC-31386;PD160828;4,4-difluoro-N-[(1S)-3-[(1S,5R)-1'-(oxan-4-ylmethyl)-2'-oxo-3'-propan-2-ylspiro[8-azabicyclo[3.2.1]octane-3,4'-imidazolidine]-8-yl]-1-phenylpropyl]cyclohexane-1-carboxamide; |
| IUPAC Name | 4,4-difluoro-N-[(1S)-3-[(1R,5S)-1'-(oxan-4-ylmethyl)-2'-oxo-3'-propan-2-ylspiro[8-azabicyclo[3.2.1]octane-3,4'-imidazolidine]-8-yl]-1-phenylpropyl]cyclohexane-1-carboxamide |
| Molecular Weight | 316.5 |
| Molecular Formula | C21H32O2 |
| Canonical SMILES | CCCCCC1=CC(=C(C(=C1)O)[C@@H]2C=C(CC[C@H]2C(C)C)C)O |
| InChI | InChI=1S/C34H50F2N4O3/c1-24(2)40-32(42)38(22-25-13-18-43-19-14-25)23-33(40)20-28-8-9-29(21-33)39(28)17-12-30(26-6-4-3-5-7-26)37-31(41)27-10-15-34(35,36)16-11-27/h3-7,24-25,27-30H,8-23H2,1-2H3,(H,37,41)/t28-,29+,30-,33?/m0/s1 |
| InChIKey | YZGXEGUSPLSQOJ-VUQZBIHUSA-N |
| Boiling Point | 755.2±60.0 °C at 760 mmHg |
| Purity | ≥98% by HPLC |
| Density | 1.2±0.1 g/cm3 |
| Solubility | Soluble in DMSO |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
