-
Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
Uprifosbuvir
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| Category | Hepatitis C Virus (HCV) |
| CAS | 1496551-77-9 |
| Description | Uprifosbuvir is an antiviral agent. Uprifosbuvir is a NS5b inhibitor developed for the research of chronic hepatitis C virus. |
Product Information
| Synonyms | Uprifosbuvir|1496551-77-9|UNII-JW31KPS26S|JW31KPS26S|IDX21437|MK-3682|propan-2-yl (2R)-2-[[[(2R,3R,4R,5R)-4-chloro-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate|Uprifosbuvir [USAN]|Uprifosbuvir (USAN/INN)|CHEMBL3833371|SCHEMBL15588599|IDX-21437|DB15206|HY-103487|CS-0027991|D10996|Q27281714|D-Alanine, N-((P(R),2'R)-2'-chloro-2'-deoxy-2'-methyl-P-phenyl-5'-uridylyl)-, 1- methylethyl ester|Propan-2-yl (2R)-2-{((R)-({(2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyloxolan-2-yl}methoxy)(phenoxy)phosphoryl)amino}propanoate|propan-2-yl N-((R)-{((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyloxolan-2-yl)methoxy}phenoxyphosphoryl)-D-alaninate |
| Molecular Weight | 545.907 |
| Molecular Formula | C22H29ClN3O9P |
| Canonical SMILES | CC(C)OC(=O)C(C)NP(=O)(OCC1C(C(C(O1)N2C=CC(=O)NC2=O)(C)Cl)O)OC3=CC=CC=C3 |
| Purity | ≥98% (HPLC) |
| Density | 1.4±0.1 g/cm3 |
| Solubility | In vitro: 10 mM in DMSO |
| Appearance | Solid powder |
| Storage | Store at -20°C |
| Complexity | 913 |
| Exact Mass | 545.1329942 |
| Index Of Refraction | 1.588 |
| Target | HCV |
| XLogP3-AA | 1.2 |
