Uprifosbuvir

Category	Hepatitis C Virus (HCV)
CAS	1496551-77-9
Description	Uprifosbuvir is an antiviral agent. Uprifosbuvir is a NS5b inhibitor developed for the research of chronic hepatitis C virus.

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Synonyms	Uprifosbuvir\|1496551-77-9\|UNII-JW31KPS26S\|JW31KPS26S\|IDX21437\|MK-3682\|propan-2-yl (2R)-2-[[[(2R,3R,4R,5R)-4-chloro-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate\|Uprifosbuvir [USAN]\|Uprifosbuvir (USAN/INN)\|CHEMBL3833371\|SCHEMBL15588599\|IDX-21437\|DB15206\|HY-103487\|CS-0027991\|D10996\|Q27281714\|D-Alanine, N-((P(R),2'R)-2'-chloro-2'-deoxy-2'-methyl-P-phenyl-5'-uridylyl)-, 1- methylethyl ester\|Propan-2-yl (2R)-2-{((R)-({(2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyloxolan-2-yl}methoxy)(phenoxy)phosphoryl)amino}propanoate\|propan-2-yl N-((R)-{((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyloxolan-2-yl)methoxy}phenoxyphosphoryl)-D-alaninate
Molecular Weight	545.907
Molecular Formula	C22H29ClN3O9P
Canonical SMILES	CC(C)OC(=O)C(C)NP(=O)(OCC1C(C(C(O1)N2C=CC(=O)NC2=O)(C)Cl)O)OC3=CC=CC=C3
Purity	≥98% (HPLC)
Density	1.4±0.1 g/cm3
Solubility	In vitro: 10 mM in DMSO
Appearance	Solid powder
Storage	Store at -20°C
Complexity	913
Exact Mass	545.1329942
Index Of Refraction	1.588
Target	HCV
XLogP3-AA	1.2