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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
TX-1918
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| Category | Human immunodeficiency Virus (HIV) |
| CAS | 503473-32-3 |
| Description | TX-1918 is a cell-permeable inhibitor of eukaryotic elongation factor-2 kinase (eEF-2K) with IC50 value of 440 nM. It also inhibits Src, PKA, PKC, and EGFR kinases at higher concentrations. |
Product Information
| Synonyms | TX-1918;503473-32-3;2-((3,5-dimethyl-4-hydroxyphenyl)-methylene)-4-cyclopentene-1,3-dione;2-[(4-hydroxy-3,5-dimethylphenyl)methylidene]cyclopent-4-ene-1,3-dione;CHEMBL437612;2-[(4-Hydroxy-3,5-dimethylphenyl)methylene]-4-cyclopentene-1,3-dione;K00011;SCHEMBL16971039;HMS3229P13;HMS3674M15;BCP16358;BDBM50375667;TX 1918;TX1918;HY-112393;CS-0045394;TX-1918; 2-((3,5-dimethyl-4-hydroxyphenyl)-methylene)-4-cyclopentene-1,3-dione; |
| IUPAC Name | 2-[(4-hydroxy-3,5-dimethylphenyl)methylidene]cyclopent-4-ene-1,3-dione |
| Molecular Weight | 426.5 |
| Molecular Formula | C21H19FN4O3S |
| Canonical SMILES | CC1=C(N2C=CN=C(C2=N1)NCC3=CC(=CC=C3)S(=O)(=O)C)C4=CC(=C(C=C4)O)F |
| InChI | InChI=1S/C14H12O3/c1-8-5-10(6-9(2)14(8)17)7-11-12(15)3-4-13(11)16/h3-7,17H,1-2H3 |
| InChIKey | YHWRISYBKMXSGJ-UHFFFAOYSA-N |
| Purity | ≥98% |
| Appearance | Crystalline Solid |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
