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Antiviral API
- Arenavirus
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Tosyl phenylalanyl chloromethyl ketone
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| Category | Human papillomavirus (HPV) |
| CAS | 402-71-1 |
| Description | Tosyl phenylalanyl chloromethyl ketone (TPCK) is an irreversible inhibitor of chymotrypsin-like proteases. It also inhibits some cysteine proteases such as caspase, papain, bromelain or ficin. |
Product Information
| Synonyms | Nα-Tosyl-L-Phenylalanine Chloromethyl Ketone; TPCK; Tos-Phe-CH2Cl |
| IUPAC Name | N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]-4-methylbenzenesulfonamide |
| Molecular Weight | 351.8 |
| Molecular Formula | C17H18ClNO3S |
| Canonical SMILES | CC1=CC=C(C=C1)S(=O)(=O)NC(CC2=CC=CC=C2)C(=O)CCl |
| InChI | InChI=1S/C17H18ClNO3S/c1-13-7-9-15(10-8-13)23(21,22)19-16(17(20)12-18)11-14-5-3-2-4-6-14/h2-10,16,19H,11-12H2,1H3/t16-/m0/s1 |
| InChIKey | MQUQNUAYKLCRME-INIZCTEOSA-N |
| Boiling Point | 509.9°C at 760 mmHg |
| Melting Point | 106-110 °C |
| Flash Point | 262.2±32.9 °C |
| Purity | ≥98% |
| Density | 1.277 g/cm3 |
| Solubility | In vitro: 10 mM in DMSO |
| Appearance | White powder |
| Application | Alkylating Agents |
| Storage | Store at 2-8 °C |
| Complexity | 475 |
| Exact Mass | 351.0695923 |
| Index Of Refraction | 1.583 |
| PSA | 71.62000 |
| Target | Ser/Thr Protease; HPV |
| Vapor Pressure | 0.0±1.3 mmHg at 25°C |
| XLogP3-AA | 3.6 |
