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TMPyP4 tosylate

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Category SARS-CoV
CAS 36951-72-1
Description TMPyP4 tosylate is a cationic porphyrin. TMPyP4 stacks with G tetrads to stabilize quadruplex DNA, and inhibits telomerase activity (IC50 ≤ 50 µM). TMPyP4 inhibits cell proliferation and induces apoptosis in three myeloma cell lines.
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Product Information

Synonyms TMP 1363
Molecular Weight 412.2
Molecular Formula C14H9IN2O3S
Canonical SMILES C1=CC(=CC=C1C(=O)NC2=NC3=CC(=C(C=C3S2)O)O)I
InChI InChI=1S/C44H37N8.4C7H8O3S/c1-49-21-13-29(14-22-49)41-33-5-7-35(45-33)42(30-15-23-50(2)24-16-30)37-9-11-39(47-37)44(32-19-27-52(4)28-20-32)40-12-10-38(48-40)43(36-8-6-34(41)46-36)31-17-25-51(3)26-18-31;4*1-6-2-4-7(5-3-6)11(8,9)10/h5-28H,1-4H3,(H,45,46,47,48);4*2-5H,1H3,(H,8,9,10)/q+3;;;;/p-3
InChIKey AKZFRMNXBLFDNN-UHFFFAOYSA-K
Purity ≥95% by HPLC
Appearance Solid
Storage 4°C, sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

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