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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
TMPyP4 tosylate
Category | SARS-CoV |
CAS | 36951-72-1 |
Description | TMPyP4 tosylate is a cationic porphyrin. TMPyP4 stacks with G tetrads to stabilize quadruplex DNA, and inhibits telomerase activity (IC50 ≤ 50 µM). TMPyP4 inhibits cell proliferation and induces apoptosis in three myeloma cell lines. |
Product Information
Synonyms | TMP 1363 |
Molecular Weight | 412.2 |
Molecular Formula | C14H9IN2O3S |
Canonical SMILES | C1=CC(=CC=C1C(=O)NC2=NC3=CC(=C(C=C3S2)O)O)I |
InChI | InChI=1S/C44H37N8.4C7H8O3S/c1-49-21-13-29(14-22-49)41-33-5-7-35(45-33)42(30-15-23-50(2)24-16-30)37-9-11-39(47-37)44(32-19-27-52(4)28-20-32)40-12-10-38(48-40)43(36-8-6-34(41)46-36)31-17-25-51(3)26-18-31;4*1-6-2-4-7(5-3-6)11(8,9)10/h5-28H,1-4H3,(H,45,46,47,48);4*2-5H,1H3,(H,8,9,10)/q+3;;;;/p-3 |
InChIKey | AKZFRMNXBLFDNN-UHFFFAOYSA-K |
Purity | ≥95% by HPLC |
Appearance | Solid |
Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |