Tilorone

Category	HIF/HIF Prolyl-Hydroxylase
CAS	27591-97-5
Description	Tilorone is a member of the class of fluoren-9-ones that is 9H-fluoren-9-one which is substituted by a 2-(diethylamino)ethoxy group at positions 2 and 7. It is a synthetic, small molecular weight compound that is an orally active interferon inducer and a selective alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) agonist, used as an antiviral drug. Its hydrochloride salt is used as an antiviral drug. It has a role as an antiviral agent, an antineoplastic agent, and an anti-inflammatory agent.

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Synonyms	Tilorone; 2,7-Bis[2-(diethylamino)ethoxy]-9-fluorenone; 2,7-Bis[2-(diethylamino)ethoxy]-9H-fluoren-9-one; Bis-DEAE-fluorenone
IUPAC Name	2,7-bis[2-(diethylamino)ethoxy]fluoren-9-one
Molecular Weight	410.55
Molecular Formula	C25H34N2O3
Canonical SMILES	CCN(CC)CCOC1=CC2=C(C=C1)C3=C(C2=O)C=C(C=C3)OCCN(CC)CC
InChI	InChI=1S/C25H34N2O3/c1-5-26(6-2)13-15-29-19-9-11-21-22-12-10-20(30-16-14-27(7-3)8-4)18-24(22)25(28)23(21)17-19/h9-12,17-18H,5-8,13-16H2,1-4H3
InChIKey	MPMFCABZENCRHV-UHFFFAOYSA-N
Boiling Point	552.3°C at 760mmHg
Flash Point	287.8±30.1 °C
Purity	95%
Density	1.102g/cm3
Appearance	Solid powder
Storage	Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month
Complexity	477
Exact Mass	410.25694295
Index Of Refraction	1.564
PSA	42.01000
Target	Influenza Virus
Vapor Pressure	0.0±1.5 mmHg at 25°C
XLogP3-AA	4.7