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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium
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| Category | Human immunodeficiency Virus (HIV) |
| CAS | 2611373-74-9 |
| Description | Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium shows substantially longer t1/2 values than tenofovir in human liver microsomes, and has strong anti-HIV activity in vitro and enhances pharmacokinetic properties in vivo. |
Product Information
| Synonyms | ammonium 3-((14-(trimethylsilyl)tetradec-13-yn-1-yl)oxy)propyl (R)-(((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate |
| IUPAC Name | azanium;[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-[3-(14-trimethylsilyltetradec-13-ynoxy)propoxy]phosphinate |
| Molecular Weight | 626.84 |
| Molecular Formula | C29H55N6O5PSi |
| Purity | ≥98% (HPLC) |
| Solubility | In vitro: 10 mM in DMSO |
| Appearance | Solid powder |
| Storage | Store at -20°C |
| Target | HIV |
