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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
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- HIF/HIF Prolyl-Hydroxylase
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- HIV Protease
- Human immunodeficiency Virus (HIV)
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- Rabies virus (RABV)
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- SARS-CoV
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- Virus Protease
- West Nile virus
- Antiviral intermediates
Surfen dihydrochloride
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| Category | Herpes simplex Virus (HSV) |
| CAS | 5424-37-3 |
| Description | Surfen dihydrochloride is a heparin sulfate antagonist that binds to heparins and glycosaminoglycans. Surfen neutralized the anticoagulant activity of both unfractionated and low molecular weight heparins and inhibited enzymatic sulfation and degradation reactions in vitro. It can maintain hESCs in a pluripotent state. |
Product Information
| Synonyms | Surfen; Aminoquinuride dihydrochloride; 1,3-Bis(4-amino-2-methyl-6-quinolyl)urea dihydrochloride |
| Molecular Weight | 445.348 |
| Molecular Formula | C21H20N6O.2HCl |
| Canonical SMILES | CC1=NC2=C(C=C(C=C2)NC(=O)NC3=CC4=C(C=C3)N=C(C=C4N)C)C(=C1)N.Cl.Cl |
| InChI | InChI=1S/C21H20N6O.2ClH/c1-11-7-17(22)15-9-13(3-5-19(15)24-11)26-21(28)27-14-4-6-20-16(10-14)18(23)8-12(2)25-20;;/h3-10H,1-2H3,(H2,22,24)(H2,23,25)(H2,26,27,28);2*1H |
| InChIKey | GKQYGRWQCWWSHN-UHFFFAOYSA-N |
| Boiling Point | 587.2°C at 760 mmHg |
| Flash Point | 308.9°C |
| Purity | >98% |
| Solubility | In vitro: 10 mM in DMSO |
| Appearance | Off-white to pink (Solid) |
| Storage | -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) |
| PSA | 118.95000 |
| Target | FGFR; HSV; VEGFR |
