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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
Sophocarpine
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| Category | Influenza Virus |
| CAS | 6483-15-4 |
| Description | Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects. Sophocarpine significantly inhibits the growth of gastric cancer (GC) cells through multiple mechanisms such as induction of autophagy, activation of cell apoptosis and down-regulation of cell survival PI3K/AKT signaling pathway. |
Product Information
| Synonyms | AS 604850; AS604850; AS-604850; 13,14-Didehydromatridin-15-one; (7aS,13aR,13bR,13cS)-2,3,6,7,7a,8,13,13a,13b,13c-decahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one |
| IUPAC Name | (1R,2R,9S,17S)-7,13-diazatetracyclo[7.7.1.02,7.013,17]heptadec-4-en-6-one |
| Molecular Weight | 246.35 |
| Molecular Formula | C15H22N2O |
| Canonical SMILES | C1CC2CN3C(CC=CC3=O)C4C2N(C1)CCC4 |
| InChI | InChI=1S/C15H22N2O/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14/h1,7,11-13,15H,2-6,8-10H2/t11-,12+,13+,15-/m0/s1 |
| InChIKey | AAGFPTSOPGCENQ-JLNYLFASSA-N |
| Boiling Point | 425.4±45.0 °C at 760 mmHg |
| Melting Point | 54~55°C |
| Flash Point | 194.0±21.1 °C |
| Purity | >98% |
| Density | 1.2±0.1 g/cm3 |
| Solubility | In vitro: 10 mM in DMSO |
| Appearance | Powder |
| Application | anti-tumor; anti-cancer; antiarrhythmic; |
| Storage | Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month |
| Complexity | 392 |
| Exact Mass | 246.173213330 |
| Index Of Refraction | 1.603 |
| PSA | 23.55000 |
| Target | Autophagy; Apoptosis; PI3K; Akt; Influenza Virus |
| Vapor Pressure | 0.0±1.0 mmHg at 25°C |
| XLogP3-AA | 1.7 |
