Sofosbuvir impurity M

Category	Hepatitis C Virus (HCV)
CAS	2095551-10-1
Description	Sofosbuvir impurity M is a diastereoisomer and impurity of Sofosbuvir, an inhibitor of HCV RNA replication with strong anti-hepatitis C virus activity.

Quotation Now

Synonyms	Isopropyl (2S)-2-{[(S)-{[(2R,3R,4S,5R)-5-(2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl)-3,4-dihydroxy-4-methyltetrahydro-2-furanyl]methoxy}(phenoxy)phosphoryl]amino}propanoate
IUPAC Name	propan-2-yl (2S)-2-[(S)-[[(2R,3R,4S,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate
Molecular Weight	527.46
Molecular Formula	C22H30N3O10P
Canonical SMILES	CC(C)OC(=O)C(C)NP(=O)(OCC1C(C(C(O1)N2C=CC(=O)NC2=O)(C)O)O)OC3=CC=CC=C3
InChI	InChI=1S/C22H30N3O10P/c1-13(2)33-19(28)14(3)24-36(31,35-15-8-6-5-7-9-15)32-12-16-18(27)22(4,30)20(34-16)25-11-10-17(26)23-21(25)29/h5-11,13-14,16,18,20,27,30H,12H2,1-4H3,(H,24,31)(H,23,26,29)/t14-,16+,18+,20+,22-,36-/m0/s1
InChIKey	WAKQLZVLNOKKHE-BFQGEBBDSA-N
Purity	≥95%
Density	1.4±0.1 g/cm3
Solubility	Soluble in DMSO
Appearance	Light yellow to yellow (Solid)
Storage	Store at -20°C
Complexity	909
Exact Mass	527.16688116
Target	HCV
XLogP3-AA	0