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Antiviral API
- Arenavirus
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Seletracetam-lithium
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| Category | Human immunodeficiency Virus (HIV) |
| Description | Seletracetam (Ucb 44212) lithium, as an analog of the antiepileptic agent Levetiracetam, is a SV2A modulator for the research of epilepsy. |
Product Information
| Molecular Weight | 239.17 |
| Molecular Formula | C10H14F2LiN2O2 |
| Purity | ≥98% (HPLC) |
| Solubility | In vitro: 10 mM in DMSO |
| Appearance | Solid powder |
| Storage | Store at -20°C |
| In Vitro | Seletracetam lithium decreases seizure activity in a number of epilepsy models and binds to the synaptic vesicle protein SV2A. Seletracetam lithium decreases synaptic responses in a time-, frequency- and concentration-dependent manner. Seletracetam lithium modifies rates of presynaptic release. Seletracetam lithium inhibits high-voltage-activated Ca2+ currents and intracellular Ca2+ increase in rat cortical neurons in vitro. |
| Target | HIV |
