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Seletracetam-lithium

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Category Human immunodeficiency Virus (HIV)
Description Seletracetam (Ucb 44212) lithium, as an analog of the antiepileptic agent Levetiracetam, is a SV2A modulator for the research of epilepsy.
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Product Information

Molecular Weight 239.17
Molecular Formula C10H14F2LiN2O2
Purity ≥98% (HPLC)
Solubility In vitro:
10 mM in DMSO
Appearance Solid powder
Storage Store at -20°C
In Vitro Seletracetam lithium decreases seizure activity in a number of epilepsy models and binds to the synaptic vesicle protein SV2A.
Seletracetam lithium decreases synaptic responses in a time-, frequency- and concentration-dependent manner.
Seletracetam lithium modifies rates of presynaptic release.
Seletracetam lithium inhibits high-voltage-activated Ca2+ currents and intracellular Ca2+ increase in rat cortical neurons in vitro.
Target HIV

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