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Antiviral API
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schisandrin A
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| Category | Virus Protease |
| CAS | 61281-38-7 |
| Description | Schizandrin A is extracted from the seeds of Schisandra chinensis (Turcz.) Baill. It significantly reduces cell apoptosis and necrosis, increases cell survival and decreases intracellular calcium concentration. It might act as a candidate therapeutic target drug used for brain ischemia and related diseases. |
Product Information
| Synonyms | schisandrin A;Schizandrin A;61281-38-7;Deoxyschisandrin;(+)-Deoxyschizandrin;(-)-Deoxyschisandrin;(-)-Deoxyschizandrin;(-)-Dimethylgomisin J;UNII-74XQL5DO3S;74XQL5DO3S;69176-53-0;Dibenzo(a,c)cyclooctene, 5,6,7,8-tetrahydro-1,2,3,10,11,12-hexamethoxy-6,7-dimethyl-, stereoisomer;Wuweizisu A;Dibenzo(a,c)cyclooctene, 5,6,7,8-tetrahydro-6,7-dimethyl-1,2,3,10,11,12-hexamethoxy-;(6R,7S)-1,2,3,10,11,12-Hexamethoxy-6,7-dimethyl-5,6,7,8-tetrahydrodibenzo[a,c][8]annulene;(9R,10s)-3,4,5,14,15,16-hexamethoxy-9,10-dimethyltricyclo[10.4.0.02,7]hexadeca-1(16),2,4,6,12,14-hexaene;DIBENZO(A,C)CYCLOOCTENE, 5,6,7,8-TETRAHYDRO-1,2,3,10,11,12-HEXAMETHOXY-6,7-DIMETHYL-, (6R,7S,12AR)-;hexamethoxy(dimethyl)[?];Di-O-methylgomisin J;SchisandrinA;Schizandrin-A;Wuweizisu-A;Deoxyschizandrin;MLS000728483;CHEMBL253908;GTPL2769;SCHEMBL2404905;SCHIZANDRIN A [WHO-DD];DTXSID10219222;CHEBI:228907;JEJFTTRHGBKKEI-OKILXGFUSA-N;HMS2227F15;Schisandrin A, analytical standard;HY-N0693;Schisandrin A, >=98% (HPLC);BDBM50485611;MFCD09026934;s3822;AKOS015960456;CCG-268845;CS-3658;1ST40207;AC-11192;AC-34831;BS-17208;DA-67486;Dibenzo(a,c)cyclooctene, 5,6,7,8-tetrahydro-1,2,3,10,11,12-hexamethoxy-6,7-dimethyl-, (6R,7S,12aS)-;SMR000445690;NCGC00385070-01!;C3501;SR-01000777559;SR-01000777559-3;Q15410931;SCHISANDRIN A (DEOXYSCHISANDRIN) (CONSTITUENT OF NORTHERN SCHISANDRA);SCHISANDRIN A (DEOXYSCHISANDRIN) (CONSTITUENT OF NORTHERN SCHISANDRA) [DSC];(6R,7S,12aR)-5,6,7,8-Tetrahydro-1,2,3,10,11,12-hexamethoxy-6,7-dimethyldibenzo[a,c]cyclooctene;(9S,10R)-3,4,5,14,15,16-hexamethoxy-9,10-dimethyltricyclo[10.4.0.0^{2,7}]hexadeca-1(16),2,4,6,12,14-hexaene;(9S,10R)-3,4,5,14,15,16-hexamethoxy-9,10-dimethyltricyclo[10.4.0.02,7]hexadeca-1(16),2,4,6,12,14-hexaene; |
| IUPAC Name | (9S,10R)-3,4,5,14,15,16-hexamethoxy-9,10-dimethyltricyclo[10.4.0.02,7]hexadeca-1(16),2,4,6,12,14-hexaene |
| Molecular Weight | 298.27 |
| Molecular Formula | C12H15FN4O4 |
| Canonical SMILES | C[C@]1([C@@H]([C@H](O[C@H]1N2C=C(C3=C(N=CN=C32)N)F)CO)O)O |
| InChI | InChI=1S/C24H32O6/c1-13-9-15-11-17(25-3)21(27-5)23(29-7)19(15)20-16(10-14(13)2)12-18(26-4)22(28-6)24(20)30-8/h11-14H,9-10H2,1-8H3/t13-,14+ |
| InChIKey | JEJFTTRHGBKKEI-OKILXGFUSA-N |
| Purity | >98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid |
| Application | As an agonist of the adiponectin receptor 2 with an IC50 value of 3.5 µM. |
| Shelf Life | As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly |
| Storage | 2 - 8 °C |
