schisandrin A

Category	Virus Protease
CAS	61281-38-7
Description	Schizandrin A is extracted from the seeds of Schisandra chinensis (Turcz.) Baill. It significantly reduces cell apoptosis and necrosis, increases cell survival and decreases intracellular calcium concentration. It might act as a candidate therapeutic target drug used for brain ischemia and related diseases.

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Synonyms	Dibenzo[a,c]cyclooctene, 5,6,7,8-tetrahydro-1,2,3,10,11,12-hexamethoxy-6,7-dimethyl-, (6R,7S,12aR)-; Dibenzo[a,c]cyclooctene, 5,6,7,8-tetrahydro-1,2,3,10,11,12-hexamethoxy-6,7-dimethyl-, stereoisomer; (6R,7S,12aR)-5,6,7,8-Tetrahydro-1,2,3,10,11,12-hexamethoxy-6,7-dimethyldibenzo[a,c]cyclooctene; Wuweizisu A; Deoxyschisandrin; (+)-Deoxyschizandrin; Schizandrin A; Deoxyschizandrin; (+)-Schisandrin A
IUPAC Name	(9S,10R)-3,4,5,14,15,16-hexamethoxy-9,10-dimethyltricyclo[10.4.0.02,7]hexadeca-1(16),2,4,6,12,14-hexaene
Molecular Weight	416.51
Molecular Formula	C24H32O6
Canonical SMILES	O(C)C1=C2C3=C(OC)C(OC)=C(OC)C=C3CC(C)C(C)CC2=CC(OC)=C1OC
InChI	InChI=1S/C24H32O6/c1-13-9-15-11-17(25-3)21(27-5)23(29-7)19(15)20-16(10-14(13)2)12-18(26-4)22(28-6)24(20)30-8/h11-14H,9-10H2,1-8H3
InChIKey	JEJFTTRHGBKKEI-UHFFFAOYSA-N
Purity	>98%
Solubility	Soluble in DMSO
Appearance	Solid
Application	As an agonist of the adiponectin receptor 2 with an IC50 value of 3.5 μM.
Shelf Life	As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Storage	2 - 8 °C