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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
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- Hepatitis B Virus (HBV)
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- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
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- Rabies virus (RABV)
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- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
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- Virus Protease
- West Nile virus
- Antiviral intermediates
SARS-CoV-2-IN-10
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| Category | SARS-CoV |
| CAS | 2722634-95-7 |
| Description | SARS-CoV-2 3C-like protease (3CLpro), an enzyme essential for viral replication. SARS-CoV-2-IN-10 may be a potent and nontoxic inhibitor of SARS-CoV-2 3CL protease. |
Product Information
| Synonyms | SARS-CoV-2-IN-10|HY-145276|CS-0370860 |
| IUPAC Name | [(4,4-difluorocyclohexyl)-phenylmethyl] N-[(2S)-4-methyl-1-oxo-1-[[(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]amino]pentan-2-yl]carbamate |
| Molecular Weight | 521.6 |
| Molecular Formula | C27H37F2N3O5 |
| Canonical SMILES | CC(C)CC(C(=O)NC(CC1CCNC1=O)C=O)NC(=O)OC(C2CCC(CC2)(F)F)C3=CC=CC=C3 |
| InChI | InChI=1S/C27H37F2N3O5/c1-17(2)14-22(25(35)31-21(16-33)15-20-10-13-30-24(20)34)32-26(36)37-23(18-6-4-3-5-7-18)19-8-11-27(28,29)12-9-19/h3-7,16-17,19-23H,8-15H2,1-2H3,(H,30,34)(H,31,35)(H,32,36)/t20-,21-,22-,23?/m0/s1 |
| InChIKey | QMWZWHYKVZAETM-FDWBJODVSA-N |
| Purity | ≥98% (HPLC) |
| Solubility | In vitro: 10 mM in DMSO |
| Appearance | Solid powder |
| Storage | Store at -20°C |
| Complexity | 793 |
| Exact Mass | 521.27012761 |
| Target | SARS-CoV |
| XLogP3-AA | 4 |
