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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
Salicylanilide
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| Category | HIV Integrase |
| CAS | 87-17-2 |
| Description | Salicylanilide has a wide range of biological activities, including antiviral, anti-inflammatory, antibacterial and so on. It inhibits HIV virus by targeting HIV-1 integrase or reverse transcriptase. It inhibits mycobacterial isocitrate lyase (ICL) and has a significant antimycobacterial effect. It can be used as an antiseptic. |
Product Information
| Synonyms | 2-Hydroxybenzanilide; 2-(N-Phenylcarboxamido)phenol; 2-(Phenylaminocarbonyl)phenol; Ansadol; Aseptolan; Hyanilid; N-Phenyl-2-hydroxybenzamide; N-Phenylsalicylamide; NSC 14881; Salicylanilid; Salicylic acid anilide; Salifebrin; Salinide; Salinidol; Salnide; Shirlan; o-Hydroxybenzanilide |
| IUPAC Name | 2-hydroxy-N-phenylbenzamide |
| Molecular Weight | 213.23 |
| Molecular Formula | C13H11NO2 |
| Canonical SMILES | C1=CC=C(C=C1)NC(=O)C2=CC=CC=C2O |
| InChI | InChI=1S/C13H11NO2/c15-12-9-5-4-8-11(12)13(16)14-10-6-2-1-3-7-10/h1-9,15H,(H,14,16) |
| InChIKey | WKEDVNSFRWHDNR-UHFFFAOYSA-N |
| Boiling Point | 294.3±23.0°C at 760 mmHg |
| Melting Point | 136-138°C |
| Flash Point | 131.8±22.6 °C |
| Purity | ≥95% |
| Density | 1.278 g/cm3 |
| Solubility | Soluble in Chloroform (Slightly), Methanol (Slightly) |
| Appearance | White to Off-white Crystalline Solid |
| Storage | Store at -20°C under inert atmosphere |
| Complexity | 236 |
| Exact Mass | 213.078978594 |
| Index Of Refraction | 1.676 |
| PSA | 49.33000 |
| Target | Some Salicylanilides and salicylamides could inhibit HIV virus by targeting of HIV-1 integrase or reverse transcriptase. Hepatitis C virus is another virus, which can be potentially afflicted by Salicylanilides on the level of two enzymes-NS3 protease and NS5B RNA polymerase. |
| Vapor Pressure | 0.0±0.6 mmHg at 25°C |
| XLogP3-AA | 3.3 |
