-
Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
Rupintrivir-d4
![{PARAM:[Name]}()](https://resource.bocsci.com/structure/rupintrivir-d4.gif)
| Category | Enterovirus (EV) |
| Description | Rupintrivir-d4 (AG7088-d4) is the deuterium labeled Rupintrivir. Rupintrivirvr (AG7088), an antiviral drug, is a potent, selective and irreversible inhibitor of human rhinovirus (HRV) 3C protease. Rupintrivirvr inhibits replication of a panel of 48 different HRV serotypes in H1-HeLA and MRC-5 cell protection assays, with a mean EC50 of 0.023 μM. Rupintrivirvr shows immune-modulatory effect. |
Product Information
| Synonyms | Rupintrivir-d4|HY-106161S|CS-0202594 |
| Molecular Weight | 602.69 |
| Molecular Formula | C31H39FN4O7 |
| Canonical SMILES | CCOC(=O)C=CC(CC1CCNC1=O)NC(=O)C(CC2=CC=C(C=C2)F)CC(=O)C(C(C)C)NC(=O)C3=NOC(=C3)C |
| Boiling Point | 866.7ºC at 760mmHg |
| Flash Point | 477.9ºC |
| Purity | ≥98% (HPLC) |
| Density | 1.213g/cm3 |
| Solubility | In vitro: 10 mM in DMSO |
| Appearance | Solid powder |
| Storage | Store at -20°C |
| Complexity | 1010 |
| Exact Mass | 602.30538474 |
| Index Of Refraction | 1.537 |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and Metabolic profiles of drugs. |
| PSA | 156.70000 |
| Target | Virus Protease; Enterovirus |
| Vapor Pressure | 1.87E-30mmHg at 25°C |
| XLogP3-AA | 3.1 |
