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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
β-Rubromycin
![{PARAM:[Name]}()](https://resource.bocsci.com/structure/27267-70-5.gif)
| Category | Reverse Transcriptases (RTs) |
| CAS | 27267-70-5 |
| Description | β-Rubromycin is a quinone antibiotic originally isolated from Streptomyces. It is effective against Gram-positive bacteria. It inhibits the growth of HMO2, KATO-III, and MCF-7 cells with GI50 values of 0.5, 0.84, and <0.1 μM, respectively. β-rubromycin also inhibits HIV-1 reverse transcriptase activity. |
Product Information
| Synonyms | beta-Rubromycin; Methyl-8,10'-dihydroxy-5,7-dimethoxy-4,9,9'-trioxo-4,4',9,9'-tetrahydro-3H,3'H-spirofuran-2,2'-pyranochromene]-7'-carboxylate |
| IUPAC Name | methyl (2S)-8',10-dihydroxy-5',7'-dimethoxy-4',9,9'-trioxospiro[3,4-dihydropyrano[4,3-g]chromene-2,2'-3H-benzo[f][1]benzofuran]-7-carboxylate |
| Molecular Weight | 536.44 |
| Molecular Formula | C27H20O12 |
| Canonical SMILES | COC1=CC(=C(C2=C1C(=O)C3=C(C2=O)OC4(C3)CCC5=C(O4)C(=C6C(=C5)C=C(OC6=O)C(=O)OC)O)O)OC |
| InChI | InChI=1S/C27H20O12/c1-34-13-8-14(35-2)20(29)18-17(13)19(28)12-9-27(39-24(12)22(18)31)5-4-10-6-11-7-15(25(32)36-3)37-26(33)16(11)21(30)23(10)38-27/h6-8,29-30H,4-5,9H2,1-3H3/t27-/m0/s1 |
| InChIKey | FXCBZGHGMRSWJD-MHZLTWQESA-N |
| Boiling Point | 874.8°C at 760 mmHg |
| Melting Point | 209-212°C |
| Flash Point | 298.9ºC |
| Purity | ≥95% |
| Density | 1.67±0.1 g/cm3 |
| Solubility | Soluble in chloroform |
| Appearance | Red Acicular Crystal |
| Storage | Store at -20°C |
| Index Of Refraction | 1.715 |
| PSA | 168.03000 |
| Target | HIV; Reverse Transcriptase; Antibiotic |
| Vapor Pressure | 2.92E-32mmHg at 25°C |
