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RSV604

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Category Respiratory syncytial Virus (RSV)
CAS 676128-63-5
Description RSV604 is a a novel benzodiazepine with submicromolar anti-RSV activity (EC50=0.86 uM).
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Product Information

Synonyms RSV-604; A-60444; RSV604; A60444; RSV 604; A 60444; 1-(2-Fluorophenyl)-3-[(3S)-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]urea;
IUPAC Name 1-(2-fluorophenyl)-3-[(3S)-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepin-3-yl]urea
Molecular Weight 388.39
Molecular Formula C22H17FN4O2
Canonical SMILES c1ccc(cc1)C2=N[C@@H](C(=O)Nc3c2cccc3)NC(=O)Nc4ccccc4F
InChI 1S/C22H17FN4O2/c23-16-11-5-7-13-18(16)25-22(29)27-20-21(28)24-17-12-6-4-10-15(17)19(26-20)14-8-2-1-3-9-14/h1-13,20H,(H,24,28)(H2,25,27,29)/t20-/m1/s1
InChIKey MTPVBMVUENFFLL-HXUWFJFHSA-N
Purity ≥98%
Solubility Soluble in DMSO
Appearance Solid Powder
Application A putative RSV nucleoprotein(N) inhibitor in phase 2 clinical trials.
Shelf Life As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Storage Store at -20 °C
Complexity 634
Exact Mass 388.13355396
PSA 82.59000
Target IC50 value: 0.86 uM(EC50)
XLogP3-AA 3.3

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