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Ritonavir-13C-d3

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Category HIV Protease
Description Ritonavir-13C,d3 (ABT 538-13C,d3) is the 13C- and deuterium labeled Ritonavir. Ritonavir (ABT 538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.61 μM.
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Product Information

Molecular Weight 724.96
Molecular Formula C37H48N6O5S2
Purity ≥98% (HPLC)
Density 1.4±0.1 g/cm3
Solubility In vitro:
10 mM in DMSO
Appearance Solid powder
Storage Store at -20°C
Index Of Refraction 1.717
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and Metabolic profiles of drugs.
Target HIV Protease; HIV; SARS-CoV; Apoptosis

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