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Rimantadine hydrochloride

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Category Influenza Virus
CAS 1501-84-4
Description Rimantadine hydrochloride, also called as Flumadine, is a nucleic acid synthesis inhibitor and an anti-influenza virus drug.
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Product Information

Synonyms 1-(1-adamantyl)ethanamine;hydrochloride
IUPAC Name 1-(1-adamantyl)ethanamine;hydrochloride
Molecular Weight 215.76
Molecular Formula C12H21N · HCl
Canonical SMILES CC(C12CC3CC(C1)CC(C3)C2)N.Cl
InChI InChI=1S/C12H21N.ClH/c1-8(13)12-5-9-2-10(6-12)4-11(3-9)7-12;/h8-11H,2-7,13H2,1H3;1H
InChIKey OZBDFBJXRJWNAV-UHFFFAOYSA-N
Boiling Point 247.8 °C at 760 mmHg
Melting Point 373-375 °C
Flash Point 99.3°C
Purity > 98.0 % (N)
Solubility Soluble to ≥ 2.5 mg/mL in DMSO
Appearance White crystalline solid
Application Used as an antiviral agent.
Storage Store in a cool and dry place and at 0 - 4 °C for short term (days to weeks) or -42 °C for long term (months to years).
Complexity 180
Exact Mass 215.1440774
In Vivo Of the total 37 children in the rimantadine group, 27% were found to have resistant isolated compared with 6% in the total group receiving acetaminophen. Furthermore, the mean inhibitory concentration of rimantadine increased with time in the rimantadine group.
PSA 26.02000
Target Influenza Virus
Vapor Pressure 0.0251mmHg at 25°C

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