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Retro-2

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Category Arenavirus
CAS 1429192-00-6
Description Retro-2 is a selective inhibitor of retrograde protein trafficking mediated by syntaxin-5 at the interface between the endosome and trans-Golgi network. It has been shown to be effective against a range of bacterial and virus pathogens, both in vitro and in animal models.
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Product Information

Synonyms RN 1-001; 2,3-Dihydro-2-(5-methyl-2-thienyl)-3-phenyl-4(1H)-quinazolinone
IUPAC Name 2-(5-methylthiophen-2-yl)-3-phenyl-1,2-dihydroquinazolin-4-one
Molecular Weight 320.4
Molecular Formula C19H16N2OS
Canonical SMILES CC1=CC=C(S1)C2NC3=CC=CC=C3C(=O)N2C4=CC=CC=C4
InChI InChI=1S/C19H16N2OS/c1-13-11-12-17(23-13)18-20-16-10-6-5-9-15(16)19(22)21(18)14-7-3-2-4-8-14/h2-12,18,20H,1H3
InChIKey BOAPXDSRULBILC-UHFFFAOYSA-N
Purity ≥98%
Solubility In vitro:
10 mM in DMSO
Appearance Crystalline Solid
Storage Powder:
-20°C: 3 years
4°C: 2 years
In solvent:
-80°C: 6 months
-20°C: 1 month
PSA 60.58000
Target Virus Protease; Arenavirus; HPV

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