Retro-2

Category	Arenavirus
CAS	1429192-00-6
Description	Retro-2 is a selective inhibitor of retrograde protein trafficking mediated by syntaxin-5 at the interface between the endosome and trans-Golgi network. It has been shown to be effective against a range of bacterial and virus pathogens, both in vitro and in animal models.

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Synonyms	RN 1-001; 2,3-Dihydro-2-(5-methyl-2-thienyl)-3-phenyl-4(1H)-quinazolinone
IUPAC Name	2-(5-methylthiophen-2-yl)-3-phenyl-1,2-dihydroquinazolin-4-one
Molecular Weight	320.4
Molecular Formula	C19H16N2OS
Canonical SMILES	CC1=CC=C(S1)C2NC3=CC=CC=C3C(=O)N2C4=CC=CC=C4
InChI	InChI=1S/C19H16N2OS/c1-13-11-12-17(23-13)18-20-16-10-6-5-9-15(16)19(22)21(18)14-7-3-2-4-8-14/h2-12,18,20H,1H3
InChIKey	BOAPXDSRULBILC-UHFFFAOYSA-N
Purity	≥98%
Solubility	In vitro: 10 mM in DMSO
Appearance	Crystalline Solid
Storage	Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month
PSA	60.58000
Target	Virus Protease; Arenavirus; HPV