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Remdesivir-d5

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Category SARS-CoV
Description Remdesivir-D5 (GS-5734-D5) is a deuterium labeled Remdesivir. Remdesivir (GS-5734) is a nucleoside analogue, with effective antiviral activity, with EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells. Remdesivir is highly effective in the control of 2019-nCoV (COVID-19) infection in vitro.
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Product Information

Synonyms GS-5734-d5
Molecular Weight 607.61
Molecular Formula C27H30D5N6O8P
Canonical SMILES C[C@H](N[P@@](OC1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])(OC[C@H]2O[C@@](C#N)(C3=CC=C4C(N)=NC=NN43)[C@H](O)[C@@H]2O)=O)C(OCC(CC)CC)=O
Purity ≥98% (HPLC)
Solubility In vitro:
10 mM in DMSO
Appearance Solid
Storage Powder:
-20°C: 3 years
4°C: 2 years
In solvent:
-80°C: 6 months
-20°C: 1 month
Complexity 1010
Exact Mass 607.25678282
Target DNA/RNA Synthesis; SARS-CoV
XLogP3-AA 1.9

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