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Raltegravir-d4

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Category HIV Integrase
CAS 2712343-38-7
Description Raltegravir-d4 is deuterium labeled Raltegravir. Raltegravir is a potent integrase (IN) inhibitor, used to treat HIV infection.
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Product Information

Synonyms Raltegravir-d4|HY-10353S|CS-0378055
Molecular Weight 448.44
Molecular Formula C20H21FN6O5
Canonical SMILES CC1=NN=C(O1)C(=O)NC(C)(C)C2=NC(=C(C(=O)N2C)O)C(=O)N(CC3=CC=CC=C3)F
Purity ≥98% (HPLC)
Solubility In vitro:
10 mM in DMSO
Appearance Solid powder
Storage Store at -20°C
Complexity 838
Exact Mass 448.18085294
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and Metabolic profiles of drugs.
Target HIV Integrase; HIV
XLogP3-AA 1.6

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