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(R)-Hydroxychloroquine

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Category SARS-CoV
CAS 137433-23-9
Description (R)-Hydroxychloroquine is the enantiomer of Hydroxychloroquine which is a medication used for the treatment of certain malaria. Hydroxychloroquine is efficiently inhibits SARS-CoV-2 infection in vitro.
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Product Information

Synonyms (R)-HCQ; (R)-(-)-Hydroxy Chloroquine Diphosphate; D-HCQ; Ethanol, 2-(((4R)-4-((7-chloro-4-quinolinyl)amino)pentyl)ethylamino)-
IUPAC Name 2-[[(4R)-4-[(7-chloroquinolin-4-yl)amino]pentyl]-ethylamino]ethanol
Molecular Weight 335.87
Molecular Formula C18H26ClN3O
Canonical SMILES CCN(CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl)CCO
InChI InChI=1S/C18H26ClN3O/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21)/t14-/m1/s1
InChIKey XXSMGPRMXLTPCZ-CQSZACIVSA-N
Melting Point >65°C (dec.)
Purity ≥98% (HPLC)
Solubility Soluble in Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Appearance Colorless to Light Yellow Oil to Sticky Solid
Storage Store at 2-8°C
Complexity 331
Exact Mass 335.1764402
Target Parasite; Toll-like Receptor (TLR); SARS-CoV; Autophagy
XLogP3-AA 3.6

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