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PLP-Snyder530

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Category SARS-CoV
Description PLP Snyder530 is a potent papain-like protease (PLpro) inhibitor with an IC50 value of 6.4 μM. PLP_Snyder530 induces conformational changes in SARS-COV-2 papain-like protease, inhibiting SARS-CoV-2 replication. PLP Snyder530 can be used for SARS-CoV-2 research.
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Product Information

Molecular Weight 372.46
Molecular Formula C24H24N2O2
Purity ≥98% (HPLC)
Solubility In vitro:
10 mM in DMSO
Appearance Solid powder
Storage Store at -20°C
In Vitro PLP Snyder530 induces conformational changes manly in BL2 region and increases the activity against PLpro.
Target IC50: 6.4 μM (papain-like protease)

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