Pleconaril

Category	Enterovirus (EV)
CAS	153168-05-9
Description	Pleconaril is a capsid function inhibitor which targets a conserved hydrophobic pocket of a major viral capsid protein called VP-1. Pleconaril inhibits attachment and virus uncoating.

Quotation Now

Synonyms	SR-263843; SR-63843; VP-63843; Win-63843; SR263843; SR63843; VP63843; Win63843; SR 263843; SR 63843; VP 63843; Win 63843; Pleconaril, Picovir. 3-[3,5-dimethyl-4-[3-(3-methyl-1,2-oxazol-5-yl)propoxy]phenyl]-5-(trifluoromethyl)-1,2,4-oxadiazole3-(3,5-dimethyl-4((3-(3-methyl-5-isoxazolyl)propyl)phenyl)-5-trifluoromethyl)-1,2,4-oxadiazolePicovirpleconaril
IUPAC Name	3-[3,5-dimethyl-4-[3-(3-methyl-1,2-oxazol-5-yl)propoxy]phenyl]-5-(trifluoromethyl)-1,2,4-oxadiazole
Molecular Weight	381.35
Molecular Formula	C18H18F3N3O3
Canonical SMILES	CC1=CC(=CC(=C1OCCCC2=CC(=NO2)C)C)C3=NOC(=N3)C(F)(F)F
InChI	1S/C18H18F3N3O3/c1-10-7-13(16-22-17(27-24-16)18(19,20)21)8-11(2)15(10)25-6-4-5-14-9-12(3)23-26-14/h7-9H,4-6H2,1-3H
InChIKey	KQOXLKOJHVFTRN-UHFFFAOYSA-N
Boiling Point	481.2±55.0 °C \| Condition: Press: 760 Torr
Melting Point	61-62°
Flash Point	244.8±31.5 °C
Purity	0.9996
Density	1.271±0.06 g/cm3
Solubility	Soluble in DMSO
Appearance	Off-White solid
Application	Picornavirus replication inhibitor. Antiviral.
Shelf Life	2 years
Storage	Store in a cool and dry place and at 0 - 4°C for short term (days to weeks) or -64°C for long term (months to years).
Complexity	471
Exact Mass	381.13002593
Index Of Refraction	1.509
PSA	74.18000
Target	Enterovirus
Vapor Pressure	0.0±1.2 mmHg at 25°C
XLogP3-AA	4.6