Pinostrobin

Category	Herpes simplex Virus (HSV)
CAS	480-37-5
Description	Pinostrobin, which can be extracted from the herbs of Cajanus cajan, may be responsible for the anti-hemorrhagic and analgesic activity (peripheral analgesic activity) of Renealmia alpinia. It leads to depolarisation of the cell potential of endothelial cells. Pinostrobin was able to exert a neuroprotective effect against Aβ(25-35)-induced neurotoxicity in PC12 cells, at least in part, via inhibiting oxidative damage and calcium overload, as well as suppressing the mitochondrial pathway of cellular apoptosis. Besides, Pinostrobin (50mg/kg/dose) possesses definite therapeutical effect in the development of lesion score.

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Synonyms	Pinostrobin;5-Hydroxy-7-methoxyflavanone;75291-74-6;5-hydroxy-7-methoxy-2-phenylchroman-4-one;480-37-5;(+/-)-Pinostrobin;5-hydroxy-7-methoxy-2-phenyl-2,3-dihydrochromen-4-one;(S)-2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4-benzopyrone;2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one;()-Pinostrobin;( inverted exclamation markA)-Pinostrobin;CHEMBL210800;SCHEMBL1485747;(2R)-5-hydroxy-7-methoxy-2-phenyl-3,4-dihydro-2H-1-benzopyran-4-one;BCP09997;LMPK12140216;MFCD00017481;AKOS016009493;DB-051500;(+/-)-Pinostrobin, >=99.0% (TLC);NS00074278;
IUPAC Name	5-hydroxy-7-methoxy-2-phenyl-2,3-dihydrochromen-4-one
Molecular Weight	270.28
Molecular Formula	C16H14O4
Canonical SMILES	O=C1C[C@@H](C2=CC=CC=C2)OC3=CC(OC)=CC(O)=C13
InChI	InChI=1S/C16H14O4/c1-19-11-7-12(17)16-13(18)9-14(20-15(16)8-11)10-5-3-2-4-6-10/h2-8,14,17H,9H2,1H3
InChIKey	ORJDDOBAOGKRJV-UHFFFAOYSA-N
Boiling Point	494.9±45.0°C (Predicted)
Melting Point	100°C
Purity	>98%
Density	1.284±0.06 g/cm3(Predicted)
Appearance	Solid
Application	Anti-hemorrhagic/analgesic
Storage	4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)