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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
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- Hepatitis B Virus (HBV)
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- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
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- Rabies virus (RABV)
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- SARS-CoV
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- Virus Protease
- West Nile virus
- Antiviral intermediates
Phloretic acid
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| Category | Influenza Virus |
| CAS | 501-97-3 |
| Description | Phloretic acid is a pheno isolated from boswellia carterii birdw. And it may have antifungal activity. |
Product Information
| Synonyms | 3-(4-Hydroxyphenyl)propionic acid; 3-(4-Hydroxyphenyl)propanoic acid |
| IUPAC Name | 3-(4-hydroxyphenyl)propanoic acid |
| Molecular Weight | 166.2 |
| Molecular Formula | C9H10O3 |
| Canonical SMILES | C1=CC(=CC=C1CCC(=O)O)O |
| InChI | InChI=1S/C9H10O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-2,4-5,10H,3,6H2,(H,11,12) |
| InChIKey | NMHMNPHRMNGLLB-UHFFFAOYSA-N |
| Boiling Point | 352.4 °C at 760 mmHg |
| Melting Point | 129-131 °C(lit.) |
| Flash Point | 181.1±17.4 °C |
| Purity | 98 % |
| Density | 1.26 g/cm3 |
| Solubility | In Vitro: DMSO : 100 mg/mL(601.76 mM;Need ultrasonic) H2O : 33.33 mg/mL(200.57 mM;Need ultrasonic) In Vivo: 1.Add each solvent one by one:PBS Solubility: 100 mg/mL (601.76 mM); Clear solution; Need ultrasonic 2.Add each solvent one by one:10% DMSO >> 40%PEG300 >> 5%Tween-80 >> 45% saline Solubility: ≥ 2.5 mg/mL (15.04 mM); Clear solution 3.Add each solvent one by one:10% DMSO >> 90% (20%SBE-β-CDin saline) Solubility: ≥ 2.5 mg/mL (15.04 mM); Clear solution 4.Add each solvent one by one:10% DMSO >> 90%corn oil Solubility: ≥ 2.5 mg/mL (15.04 mM); Clear solution |
| Appearance | Powder |
| Application | 3-(4-Hydroxyphenyl)propionic Acid is an antioxidant. |
| Storage | Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month |
| Animal Admin | Indicated mice receive 200 mM Desaminotyrosine dissolved in Kool-Aid in the drinking water (control animals receive Kool-Aid alone). Indicated mice receive poly(IC) injections of 1 mg/kg for vancomycin, neomycin, ampicillin, and metronidazole (VNAM) treated mice or 5 mg/kg for all other mice intraperitoneally daily for 4 days, and then mice are scarified on day five at which time serum is collected. |
| Complexity | 148 |
| Exact Mass | 166.062994177 |
| Index Of Refraction | 1.580 |
| In Vivo | Wild-type mice produce nanomoles of Desaminotyrosine per gram of feces and have picomolar quantities of Desaminotyrosine in the serum. Desaminotyrosine (200 mM) treatment before influenza infection, protects from influenza by type I interferon (IFN) signaling, with no effect on weight loss or survival in mice with or without vancomycin, neomycin, ampicillin, and metronidazole (VNAM). Desaminotyrosine enhances type I IFN in macrophages via type I IFN amplification in mice. |
| PSA | 57.53000 |
| Target | Human Endogenous Metabolite |
| Vapor Pressure | 0.0±0.8 mmHg at 25°C |
| XLogP3-AA | 1.2 |
