-
Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
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- Flavivirus
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- Hepatitis B Virus (HBV)
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- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
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- Influenza Virus
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- Rabies virus (RABV)
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- Reverse Transcriptases (RTs)
- SARS-CoV
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- Virus Protease
- West Nile virus
- Antiviral intermediates
PF-00835231
![{PARAM:[Name]}()](https://resource.bocsci.com/structure/870153-29-0.gif)
| Category | SARS-CoV |
| CAS | 870153-29-0 |
| Description | PF-00835231 is a SARS-CoV-2 3CLpro inhibitor that has the potential as the treatment for COVID-19. |
Product Information
| Synonyms | PF 00835231; PF00835231 |
| IUPAC Name | N-[(2S)-1-[[(2S)-4-hydroxy-3-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide |
| Molecular Weight | 472.53 |
| Molecular Formula | C24H32N4O6 |
| Canonical SMILES | CC(C)CC(C(=O)NC(CC1CCNC1=O)C(=O)CO)NC(=O)C2=CC3=C(N2)C=CC=C3OC |
| InChI | InChI=1S/C24H32N4O6/c1-13(2)9-18(23(32)27-17(20(30)12-29)10-14-7-8-25-22(14)31)28-24(33)19-11-15-16(26-19)5-4-6-21(15)34-3/h4-6,11,13-14,17-18,26,29H,7-10,12H2,1-3H3,(H,25,31)(H,27,32)(H,28,33)/t14-,17-,18-/m0/s1 |
| InChIKey | QDIMHKWNHMVDJB-WBAXXEDZSA-N |
| Purity | 98.58% |
| Solubility | In vitro: 10 mM in DMSO |
| Appearance | White to off-white (Solid) |
| Storage | Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month |
| Complexity | 760 |
| Exact Mass | 472.23218475 |
| Target | SARS-CoV |
| XLogP3-AA | 1.6 |
