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Peramivir Trihydrate

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Category Influenza Virus
CAS 1041434-82-5
Description Peramivir Trihydrate is a trihydrate of the anti-infection agent peramivir (RWJ-270201,BCX-1812) which is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.
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Product Information

Synonyms BCX-1812; RWJ-270201; S-021812; BCX 1812; RWJ 270201; S 021812; BCX1812; RWJ270201; S021812
IUPAC Name (1S,2S,3S,4R)-3-[(1S)-1-acetamido-2-ethylbutyl]-4-(diaminomethylideneamino)-2-hydroxycyclopentane-1-carboxylic acid;trihydrate
Molecular Weight 382.45
Molecular Formula C15H28N4O4.3H2O
Canonical SMILES CCC(CC)C(C1C(CC(C1O)C(=O)O)N=C(N)N)NC(=O)C.O.O.O
InChI InChI=1S/C15H28N4O4.3H2O/c1-4-8(5-2)12(18-7(3)20)11-10(19-15(16)17)6-9(13(11)21)14(22)23;;;/h8-13,21H,4-6H2,1-3H3,(H,18,20)(H,22,23)(H4,16,17,19);3*1H2/t9-,10+,11+,12-,13+;;;/m0.../s1
InChIKey RFUCJKFZFXNIGB-ZBBHRWOZSA-N
Purity >98%
Solubility 5%TFA: 3 mg/mL (7.84 mM)
DMSO: 0.2 mg/mL (0.52 mM)
Water: Insoluble
Appearance Solid powder
Application Antiviral Agents
Storage Powder:
3 years -20°C
In solvent:
2 years -80°C
Complexity 460
Exact Mass 382.24274944
PSA 179.71000
Target Influenza Virus

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