-
Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
Peramivir Trihydrate
Category | Influenza Virus |
CAS | 1041434-82-5 |
Description | Peramivir Trihydrate is a trihydrate of the anti-infection agent peramivir (RWJ-270201,BCX-1812) which is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM. |
Product Information
Synonyms | BCX-1812; RWJ-270201; S-021812; BCX 1812; RWJ 270201; S 021812; BCX1812; RWJ270201; S021812 |
IUPAC Name | (1S,2S,3S,4R)-3-[(1S)-1-acetamido-2-ethylbutyl]-4-(diaminomethylideneamino)-2-hydroxycyclopentane-1-carboxylic acid;trihydrate |
Molecular Weight | 382.45 |
Molecular Formula | C15H28N4O4.3H2O |
Canonical SMILES | CCC(CC)C(C1C(CC(C1O)C(=O)O)N=C(N)N)NC(=O)C.O.O.O |
InChI | InChI=1S/C15H28N4O4.3H2O/c1-4-8(5-2)12(18-7(3)20)11-10(19-15(16)17)6-9(13(11)21)14(22)23;;;/h8-13,21H,4-6H2,1-3H3,(H,18,20)(H,22,23)(H4,16,17,19);3*1H2/t9-,10+,11+,12-,13+;;;/m0.../s1 |
InChIKey | RFUCJKFZFXNIGB-ZBBHRWOZSA-N |
Purity | >98% |
Solubility | 5%TFA: 3 mg/mL (7.84 mM) DMSO: 0.2 mg/mL (0.52 mM) Water: Insoluble |
Appearance | Solid powder |
Application | Antiviral Agents |
Storage | Powder: 3 years -20°C In solvent: 2 years -80°C |
Complexity | 460 |
Exact Mass | 382.24274944 |
PSA | 179.71000 |
Target | Influenza Virus |