Peramivir

Category	Influenza Virus
CAS	330600-85-6
Description	Peramivir is an antiviral inhibitor with an IC50 of median 0.09 nM. It prevents the virus from infecting cells.

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Synonyms	BCX 1812; BCX1812; BCX-1812 (1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylbutyl]-4-[(aminoiminomethyl)amino]-2-hydroxycyclopentanecarboxylic Acid
IUPAC Name	(1S,2S,3S,4R)-3-[(1S)-1-acetamido-2-ethylbutyl]-4-(diaminomethylideneamino)-2-hydroxycyclopentane-1-carboxylic acid
Molecular Weight	328.41
Molecular Formula	C15H28N4O4
Canonical SMILES	CCC(CC)C(C1C(CC(C1O)C(=O)O)N=C(N)N)NC(=O)C
InChI	InChI=1S/C15H28N4O4/c1-4-8(5-2)12(18-7(3)20)11-10(19-15(16)17)6-9(13(11)21)14(22)23/h8-13,21H,4-6H2,1-3H3,(H,18,20)(H,22,23)(H4,16,17,19)/t9-,10+,11+,12-,13+/m0/s1
InChIKey	RQDFNLINLXZLB-CKIKVBCHSA-N
Melting Point	170-172 °C
Purity	≥98.0%
Density	1.39 g/cm3
Solubility	Soluble in DMSO
Appearance	White to Off-White Solid
Application	A new antiviral agent for influenza treatment, could be used as neuraminidase inhibitor for treating human and avian influenza.
Shelf Life	As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Storage	Store at -20 °C
Complexity	460
Exact Mass	328.21105539
Index Of Refraction	1.614
PSA	151.03000
Target	IC50 values ranging form 0.9 to 4.3 nM for nine influenza virus neuraminidase subtypes.
XLogP3-AA	0