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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
para-METHOXY CINNAMIC ALDEHYDE (PMCA)
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| Category | Respiratory syncytial Virus (RSV) |
| CAS | 1963-36-6 |
| Description | 4-Methoxycinnamaldehyde (p-Methoxycinnamaldehyde), an active constituent of Agastache rugosa, exhibits cytoprotective activity against respiratory syncytial virus (RSV) in human larynx carcinoma cell line. It effectively inhibits cytopathic effect of RSV with an estimated IC50 of 0.055 μg/mL. |
Product Information
| Synonyms | (* Alt. CAS #) CAS: 24680-50-0; trans-p-Methoxy cinammic aldehyde, 2-Propenal, 3-(4-methoxyphenyl)-, 3-(4-Methoxyphenyl)-2-propenal, 3-(4-Methoxyphenyl)acrylaldehyde, 4-Methoxycinnamaldehyde, p-Methoxycinnamaldehyde, para-METHOXY CINNAMIC ALDEHYDE (PMCA) |
| Molecular Weight | 162.18 |
| Molecular Formula | C10H10O2 |
| Canonical SMILES | COC1=CC=C(C=C1)C=CC=O |
| Boiling Point | 262.85 C (EPI 4.0) |
| Melting Point | 55-60°C(lit.) |
| Flash Point | 146.5°C |
| Purity | 98.0% |
| Density | 1.068 g/cm³ |
| Solubility | Insoluble in water; soluble in alcohol. |
| Appearance | yellow crystalline solid |
| Shelf Life | 96 months from manufacture date |
| Storage | Store tightly sealed under inert gas in a cool, well-ventilated area. |
| Assay | 0.98 |
| Complexity | 155 |
| Exact Mass | 162.068085 |
| Index Of Refraction | 1.559 |
| In Vitro | 4-Methoxycinnamaldehyde inhibited human respiratory syncytial virus in a human larynx carcinoma cell line. 4-Methoxycinnamaldehyde might be helpful to manage the disease induced by RSV infection. |
| PSA | 26.30000 |
| Target | RSV; IFN |
| Vapor Pressure | 0.0±0.7 mmHg at 25°C |
| XLogP3-AA | 1.8 |
