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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
Oltipraz-d3
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| Category | Human immunodeficiency Virus (HIV) |
| CAS | 2012598-51-3 |
| Description | Oltipraz-d3 (RP 35972-d3) is the deuterium labeled Oltipraz. Oltipraz has an inhibitory effect on HIF-1α activation in a time-dependent manner, completely abrogating HIF-1α induction at ≥10 μM concentrations, the IC50 of Oltipraz for HIF-1α inhibition is 10 μM. Oltipraz is a potent Nrf2 activator. |
Product Information
| Synonyms | Oltipraz-d3|HY-12519S|CS-0373484 |
| Molecular Weight | 229.36 |
| Molecular Formula | C8H6N2S3 |
| Canonical SMILES | CC1=C(SSC1=S)C2=NC=CN=C2 |
| Boiling Point | 408.1±55.0 °C at 760 mmHg |
| Melting Point | 165-166ºC |
| Flash Point | 200.6±31.5 °C |
| Purity | ≥98% (HPLC) |
| Density | 1.5±0.1 g/cm3 |
| Solubility | In vitro: 10 mM in DMSO |
| Appearance | Solid powder |
| Storage | Store at -20°C |
| Complexity | 262 |
| Exact Mass | 228.98814196 |
| Index Of Refraction | 1.760 |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and Metabolic profiles of drugs. |
| PSA | 114.35000 |
| Target | HIF/HIF Prolyl-Hydroxylase; HIV; Keap1-Nrf2 |
| Vapor Pressure | 0.0±0.9 mmHg at 25°C |
| XLogP3-AA | 1.1 |
