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Octaethylene glycol monododecyl ether

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Category Influenza Virus
CAS 3055-98-9
Description Octaethylene glycol monododecyl ether, a non-ionic surfactant formed by the ethoxylation of dodecanol (lauryl alcohol), is a non-ionic detergent for the solubilization of membrane bound proteins, as well as the viral membranes of intact influenza viruses.
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Product Information

Synonyms C12E8; 3,6,9,12,15,18,21,24-Octaoxahexatriacontan-1-ol; Dodecyloctaethyleneglycol monoether; N-Dodecyl octaethylene glycol monoether; Octaethylene Glycol Mono-N-Dodecyl Ether
IUPAC Name 2-[2-[2-[2-[2-[2-[2-(2-dodecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Molecular Weight 538.75
Molecular Formula C28H58O9
Canonical SMILES CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCO
InChI InChI=1S/C28H58O9/c1-2-3-4-5-6-7-8-9-10-11-13-30-15-17-32-19-21-34-23-25-36-27-28-37-26-24-35-22-20-33-18-16-31-14-12-29/h29H,2-28H2,1H3
InChIKey YYELLDKEOUKVIQ-UHFFFAOYSA-N
Boiling Point 585.5±45.0°C (Predicted)
Melting Point 30°C
Purity 95%
Density 0.984-0.992 g/mL at 35°C
Solubility Soluble in Chloroform (Slightly), Methanol (Slightly)
Appearance White to Off-white Low-melting Solid
Storage Store at RT under inert atmosphere
In Vitro Octaethylene glycol monododecyl ether (C12E8) has been shown to solubilize the viral membrane of intact influenza virus
The mechanism of solubilization of the viral membrane is based on the accumulation of C12E8 molecules outside the membrane until the formation of micelles leading to the extraction of membrane constituents.
In Vivo Octaethylene glycol monododecyl ether (C12E8) has been shown to solubilize the viral membrane of intact influenza virus.
Target Influenza Virus

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