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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
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- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
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- Influenza Virus
- Nipah virus
- Orthopoxvirus
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- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
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- Virus Protease
- West Nile virus
- Antiviral intermediates
Octaethylene glycol monododecyl ether
Category | Influenza Virus |
CAS | 3055-98-9 |
Description | Octaethylene glycol monododecyl ether, a non-ionic surfactant formed by the ethoxylation of dodecanol (lauryl alcohol), is a non-ionic detergent for the solubilization of membrane bound proteins, as well as the viral membranes of intact influenza viruses. |
Product Information
Synonyms | C12E8; 3,6,9,12,15,18,21,24-Octaoxahexatriacontan-1-ol; Dodecyloctaethyleneglycol monoether; N-Dodecyl octaethylene glycol monoether; Octaethylene Glycol Mono-N-Dodecyl Ether |
IUPAC Name | 2-[2-[2-[2-[2-[2-[2-(2-dodecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol |
Molecular Weight | 538.75 |
Molecular Formula | C28H58O9 |
Canonical SMILES | CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCO |
InChI | InChI=1S/C28H58O9/c1-2-3-4-5-6-7-8-9-10-11-13-30-15-17-32-19-21-34-23-25-36-27-28-37-26-24-35-22-20-33-18-16-31-14-12-29/h29H,2-28H2,1H3 |
InChIKey | YYELLDKEOUKVIQ-UHFFFAOYSA-N |
Boiling Point | 585.5±45.0°C (Predicted) |
Melting Point | 30°C |
Purity | 95% |
Density | 0.984-0.992 g/mL at 35°C |
Solubility | Soluble in Chloroform (Slightly), Methanol (Slightly) |
Appearance | White to Off-white Low-melting Solid |
Storage | Store at RT under inert atmosphere |
In Vitro | Octaethylene glycol monododecyl ether (C12E8) has been shown to solubilize the viral membrane of intact influenza virus The mechanism of solubilization of the viral membrane is based on the accumulation of C12E8 molecules outside the membrane until the formation of micelles leading to the extraction of membrane constituents. |
In Vivo | Octaethylene glycol monododecyl ether (C12E8) has been shown to solubilize the viral membrane of intact influenza virus. |
Target | Influenza Virus |