Niazinin

Category	SARS-CoV
CAS	147821-57-6
Description	Niazinin is a natural compound isolated from the leaves of Moringa oleifera Lam, showing antileishmanial activity against promastigotes of Leishmania donavani.

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Synonyms	Niazinin A
IUPAC Name	O-methyl N-[[4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyphenyl]methyl]carbamothioate
Molecular Weight	343.39
Molecular Formula	C15H21NO6S
Canonical SMILES	CC1C(C(C(C(O1)OC2=CC=C(C=C2)CNC(=S)OC)O)O)O
InChI	InChI=1S/C15H21NO6S/c1-8-11(17)12(18)13(19)14(21-8)22-10-5-3-9(4-6-10)7-16-15(23)20-2/h3-6,8,11-14,17-19H,7H2,1-2H3,(H,16,23)/t8-,11-,12+,13+,14-/m0/s1
InChIKey	ZOIAMMQYAZSWRX-CNJBRALLSA-N
Purity	98.0%
Solubility	In vitro: 10 mM in DMSO
Appearance	Oil
Storage	4°C, protect from light * In solvent : -80°C, 6 months -20°C, 1 month (protect from light)
Complexity	390
Exact Mass	343.10895856
In Vitro	Niazinin, is cytotoxic at substantially higher concentration (CC50 of 31.6 µM) than its antileishmanial concentration (IC50 of 5.25 µM).
Target	Parasite; SARS-CoV
XLogP3-AA	0.4