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N-METHYLISATIN-3-THIOSEMICARBAZONE

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Category SARS-CoV
CAS 1910-68-5
Description Methisazone (Marboran) is an antiviral agent that works by inhibiting mRNA and protein synthesis. Methisazone is also a SARS-CoV-2 (COVID-19) inhibitor. Methisazone is mainly used in pox viruses.
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Product Information

Synonyms N-METHYLISATIN-3-THIOSEMICARBAZONE; 1-methylindole-2,3-dione3-(thiosemicarbazone); 2-(1,2-dihydro-1-methyl-2-oxo-3h-indole-3-ylidene)-hydrazinecarbothioamid; 33t57; 3-dione,1-methyl-indole-3-(thiosemicarbazone); bw33-t-57; compound33t57; kemoviran
IUPAC Name (2-hydroxy-1-methylindol-3-yl)iminothiourea
Molecular Weight 234.28
Molecular Formula C10H10N4OS
Canonical SMILES CN1C2=CC=CC=C2C(=C1O)N=NC(=S)N
InChI InChI=1S/C10H10N4OS/c1-14-7-5-3-2-4-6(7)8(9(14)15)12-13-10(11)16/h2-5,15H,1H3,(H2,11,16)
InChIKey TTZUCVNWOZLIGL-UHFFFAOYSA-N
Purity ≥98% (HPLC)
Solubility Soluble in DMSO
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -23 C for long term (months to years).
Complexity 309
Exact Mass 234.05753213
Target SARS-CoV; Orthopoxvirus
XLogP3-AA 2

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