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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
N-METHYLISATIN-3-THIOSEMICARBAZONE
Category | SARS-CoV |
CAS | 1910-68-5 |
Description | Methisazone (Marboran) is an antiviral agent that works by inhibiting mRNA and protein synthesis. Methisazone is also a SARS-CoV-2 (COVID-19) inhibitor. Methisazone is mainly used in pox viruses. |
Product Information
Synonyms | N-METHYLISATIN-3-THIOSEMICARBAZONE; 1-methylindole-2,3-dione3-(thiosemicarbazone); 2-(1,2-dihydro-1-methyl-2-oxo-3h-indole-3-ylidene)-hydrazinecarbothioamid; 33t57; 3-dione,1-methyl-indole-3-(thiosemicarbazone); bw33-t-57; compound33t57; kemoviran |
IUPAC Name | (2-hydroxy-1-methylindol-3-yl)iminothiourea |
Molecular Weight | 234.28 |
Molecular Formula | C10H10N4OS |
Canonical SMILES | CN1C2=CC=CC=C2C(=C1O)N=NC(=S)N |
InChI | InChI=1S/C10H10N4OS/c1-14-7-5-3-2-4-6(7)8(9(14)15)12-13-10(11)16/h2-5,15H,1H3,(H2,11,16) |
InChIKey | TTZUCVNWOZLIGL-UHFFFAOYSA-N |
Purity | ≥98% (HPLC) |
Solubility | Soluble in DMSO |
Appearance | Solid powder |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -23 C for long term (months to years). |
Complexity | 309 |
Exact Mass | 234.05753213 |
Target | SARS-CoV; Orthopoxvirus |
XLogP3-AA | 2 |