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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
Moroxydine
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| Category | Influenza Virus |
| CAS | 3731-59-7 |
| Description | Moroxydine is used as an antiviral drug against multiple DNA and RNA virus. |
Product Information
| Synonyms | N-(diaminomethylidene)-4-morpholinecarboximidamide; N-(diaminomethylidene)morpholine-4-carboximidamide |
| IUPAC Name | N-(diaminomethylidene)morpholine-4-carboximidamide |
| Molecular Weight | 171.20 |
| Molecular Formula | C6H13N5O |
| Canonical SMILES | C1COCCN1C(=N)N=C(N)N |
| InChI | InChI=1S/C6H13N5O/c7-5(8)10-6(9)11-1-3-12-4-2-11/h1-4H2,(H5,7,8,9,10) |
| InChIKey | KJHOZAZQWVKILO-UHFFFAOYSA-N |
| Boiling Point | 327 °C at 760 mmHg |
| Melting Point | 211-214 °C (lit.) |
| Flash Point | 151.6°C |
| Purity | 97 % |
| Density | 1.51 g/cm3 |
| Solubility | In vitro: H2O:≥44mg / mL(211.88 mM) |
| Appearance | Solid powder |
| Application | Antiviral Agents |
| Storage | Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month |
| Complexity | 192 |
| Exact Mass | 171.11201006 |
| Index Of Refraction | 1.661 |
| In Vitro | In grass carp reovirus-infected CIK cells, virus-related BCl-2- and Caspase-mediated Apoptosis is reduced by 50% following treatment with 6.3 µg/ml of moroxydine for 96 hours. In gibel carp housed at 25°C, the absorption and elimination half-lives are 2.02 and 4.22 hours, respectively, following oral administration of a 10 mg/kg dose of moroxydine. |
| PSA | 98.22000 |
| Target | DNA and RNA viruses including measles, herpes simplex, varicella zoster, and hepatitis C. |
| XLogP3-AA | -1.6 |
