Monocaprin

Category	Herpes simplex Virus (HSV)
CAS	26402-22-2
Description	Monocaprin is effective against enveloped viruses, certain bacteria, and the yeast Candida albicans. It can be used as a lipid excipient in drug delivery system.

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Synonyms	2,3-Dihydroxypropyl decanoate; Glyceryl caprate; 1-Decanoyl-rac-glycerol
Molecular Weight	246.347
Molecular Formula	C13H26O4
Canonical SMILES	CCCCCCCCCC(=O)OCC(CO)O
InChI	InChI=1S/C13H26O4/c1-2-3-4-5-6-7-8-9-13(16)17-11-12(15)10-14/h12,14-15H,2-11H2,1H3
InChIKey	LKUNXBRZDFMZOK-UHFFFAOYSA-N
Melting Point	53°C
Flash Point	129.6°C
Purity	≥98%
Density	1.017 g/cm³
Solubility	In Vitro: DMSO : 41.67 mg/mL(169.16 mM;Need ultrasonic) In Vivo: 1.Add each solvent one by one:10% DMSO >> 40%PEG300 >> 5%Tween-80 >> 45% saline Solubility: ≥ 2.08 mg/mL (8.44 mM); Clear solution 2.Add each solvent one by one:10% DMSO >> 90%corn oil Solubility: ≥ 2.08 mg/mL (8.44 mM); Clear solution
Appearance	Clear semi-solid
Storage	-20°C
Index Of Refraction	1.466
In Vitro	Glyceryl monocaprate (Monolaurin) has an antimicrobial activity against gram-positive ATCC SA 29123.
In Vivo	Glyceryl monocaprate (Monolaurin) combines with low-dose doxycycline offers an effective treatment for herpes labialiss, significantly reducing time to healing and pain compared with the placebo and monocaprin alone.
PSA	66.76000
Target	Bacterial; HSV
Vapor Pressure	5.96E-07mmHg at 25°C