ML324

Category	Cytomegalovirus (CMV)
CAS	1222800-79-4
Description	ML324 exhibits good Caco-2 cell permeability, and possesses excellent microsomal stability in the presence of both mouse and rat liver microsomes.

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Synonyms	ML-324; ML 324; ML324; CID-44143209; CID 44143209; CID44143209.
IUPAC Name	N-[3-(dimethylamino)propyl]-4-(8-hydroxyquinolin-6-yl)benzamide
Molecular Weight	349.43
Molecular Formula	C21H23N3O2
Canonical SMILES	CN(C)CCCNC(=O)C1=CC=C(C=C1)C2=CC(=C3C(=C2)C=CC=N3)O
InChI	InChI=1S/C21H23N3O2/c1-24(2)12-4-11-23-21(26)16-8-6-15(7-9-16)18-13-17-5-3-10-22-20(17)19(25)14-18/h3,5-10,13-14,25H,4,11-12H2,1-2H3,(H,23,26)
InChIKey	QDBVSOZTVKXUES-UHFFFAOYSA-N
Boiling Point	590.1±50.0 °C at 760 mmHg
Flash Point	310.7±30.1 °C
Purity	>98%
Density	1.2±0.1 g/cm3
Solubility	In vitro: 10 mM in DMSO
Appearance	Yellow to gray (Solid)
Storage	Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month
Complexity	449
Exact Mass	349.17902698
Index Of Refraction	1.629
In Vitro	ML324 produces a significant reduction in Aa-LPS-induced osteoclastogenesis in osteoclast progenitors
Target	IC50: JMJD2, 4.9 μM (KDM4B)
Vapor Pressure	0.0±1.7 mmHg at 25°C
XLogP3-AA	3.1