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Miltefosine-d9

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Category Human immunodeficiency Virus (HIV)
Description Miltefosine-d9 (HePC-d9) is the deuterium labeled Miltefosine. Miltefosine is a broad spectrum antimicrobial, anti-leishmanial, phospholipid agent acting by inhibiting the PI3K/Akt activity. Miltefosine is an inhibitor of CTP-phosphocholine cytidyltransferase (CCT).
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Product Information

Synonyms Miltefosine-d9|HY-13685S|CS-0372468
Molecular Weight 416.62
Molecular Formula C21H46NO4P
Canonical SMILES CCCCCCCCCCCCCCCCOP(=O)([O-])OCC[N+](C)(C)C
Melting Point 232-234°C
Purity ≥98% (HPLC)
Solubility In vitro:
10 mM in DMSO
Appearance Solid powder
Storage Store at -20°C
Complexity 363
Exact Mass 416.37293666
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and Metabolic profiles of drugs.
PSA 68.40000
Target Akt; HIV
XLogP3-AA 6.7

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