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Antiviral API
- Arenavirus
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- Antiviral intermediates
Mefloquine Hydrochloride
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| Category | SARS-CoV |
| CAS | 51773-92-3 |
| Description | Mefloquine HCl is a blood schizonticide by inhibiting hemozoin formation, used as an antimalarial drug. |
Product Information
| Synonyms | (αS)-rel-α-(2R)-2-Piperidinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol; (+/-)-Mefloquine Hydrochloride; Loriam; Mefloquin Hydrochloride; Mefloquine Hydrochloride; NSC 157387; Ro 21-5998/001; WR 142490 |
| IUPAC Name | (S)-[2,8-bis(trifluoromethyl)quinolin-4-yl]-[(2R)-piperidin-2-yl]methanol;hydrochloride |
| Molecular Weight | 414.77 |
| Molecular Formula | C17H17ClF6N2O |
| Canonical SMILES | C1CCNC(C1)C(C2=CC(=NC3=C2C=CC=C3C(F)(F)F)C(F)(F)F)O.Cl |
| InChI | InChI=1S/C17H16F6N2O.ClH/c18-16(19,20)11-5-3-4-9-10(15(26)12-6-1-2-7-24-12)8-13(17(21,22)23)25-14(9)11;/h3-5,8,12,15,24,26H,1-2,6-7H2;1H/t12-,15+;/m1./s1 |
| InChIKey | WESWYMRNZNDGBX-YLCXCWDSSA-N |
| Boiling Point | 260.6±9.0 °C at 760 mmHg |
| Melting Point | >253°C (dec.) |
| Flash Point | 109.7±13.1 °C |
| Purity | >98% |
| Density | 1.2±0.1 g/cm3 |
| Solubility | In vitro: 10 mM in DMSO |
| Appearance | White Solid |
| Application | Antimalarials |
| Storage | 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) |
| Complexity | 483 |
| Exact Mass | 414.0933598 |
| Index Of Refraction | 1.529 |
| Target | SARS-CoV |
| Vapor Pressure | 0.0±0.5 mmHg at 25°C |
