Levofloxacin

Category	Orthopoxvirus
CAS	100986-85-4
Description	Levofloxacin is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Levofloxacin achieves higher concentrations in the serum and tissue of mice than does ciprofloxacin.

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Synonyms	Fluoroquinolone
IUPAC Name	(2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
Molecular Weight	361.37
Molecular Formula	C18H20FN3O4
Canonical SMILES	CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O
InChI	InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/t10-/m0/s1
InChIKey	GSDSWSVVBLHKDQ-JTQLQIEISA-N
Boiling Point	571.5±50.0 °C at 760 mmHg
Melting Point	218°C
Flash Point	299.4±30.1 °C
Purity	>98%
Density	1.5±0.1 g/cm3
Solubility	In vitro: 10 mM in DMSO
Appearance	Pale Yellow Solid
Application	Anti-bacterial agents; anti-infective agents, Urinary; nucleic acid synthesis inhibitors
Storage	4°C, protect from light * In solvent : -80°C, 6 months -20°C, 1 month (protect from light)
Complexity	634
Exact Mass	361.14378429
Index Of Refraction	1.670
PSA	75.01000
Target	Topoisomerase; DNA/RNA Synthesis; Antibiotic; Bacterial; Orthopoxvirus
Vapor Pressure	0.0±1.7 mmHg at 25°C
XLogP3-AA	-0.4