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Levofloxacin

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Category Orthopoxvirus
CAS 100986-85-4
Description Levofloxacin is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Levofloxacin achieves higher concentrations in the serum and tissue of mice than does ciprofloxacin.
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Product Information

Synonyms Fluoroquinolone
IUPAC Name (2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
Molecular Weight 361.37
Molecular Formula C18H20FN3O4
Canonical SMILES CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O
InChI InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/t10-/m0/s1
InChIKey GSDSWSVVBLHKDQ-JTQLQIEISA-N
Boiling Point 571.5±50.0 °C at 760 mmHg
Melting Point 218°C
Flash Point 299.4±30.1 °C
Purity >98%
Density 1.5±0.1 g/cm3
Solubility In vitro:
10 mM in DMSO
Appearance Pale Yellow Solid
Application Anti-bacterial agents; anti-infective agents, Urinary; nucleic acid synthesis inhibitors
Storage 4°C, protect from light
* In solvent :
-80°C, 6 months
-20°C, 1 month (protect from light)
Complexity 634
Exact Mass 361.14378429
Index Of Refraction 1.670
PSA 75.01000
Target Topoisomerase; DNA/RNA Synthesis; Antibiotic; Bacterial; Orthopoxvirus
Vapor Pressure 0.0±1.7 mmHg at 25°C
XLogP3-AA -0.4

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