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Larixyl acetate

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Category Human papillomavirus (HPV)
CAS 4608-49-5
Description Larixyl acetate is a potent and selective TRPC6 inhibitor with IC50 values of 0.58 μM and 6.83 μM against hTRPC6-YFP and hTRPC3-YFP, respectively. Larixyl acetate prevents HPV and is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction.
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Product Information

Synonyms LARIXYL ACETATE; (13S)-6α-Acetoxylabda-8(17),14-diene-13-ol; (1S,8aβ)-4α-[(S)-3-Methyl-3-hydroxy-4-pentenyl]decahydro-4aα,8,8-trimethyl-3-methylenenaphthalen-1β-ol 1-acetate; (1S,8aβ)-4α-[(S)-3-Methyl-3-hydroxy-4-pentenyl]decahydro-4aα,8,8-trimethyl-3-methy
Molecular Weight 348.52
Molecular Formula C22H36O3
Canonical SMILES CC(=O)OC1CC(=C)C(C2(C1C(CCC2)(C)C)C)CCC(C)(C=C)OC(=O)C
Melting Point 82ºC
Purity ≥98% (HPLC)
Density 1.00±0.1 g/cm3 (20ºC 760 Torr)
Solubility Soluble in ethanol and methan
Appearance Solid powder
Storage Desiccate at -20°C
Complexity 649
Exact Mass 390.27700969
Index Of Refraction 1.4826 (589.3 nm, 20℃)
PSA 46.53000
Target hTRPC6: 0.58 μM (IC50)
hTRPC3: 6.83 μM (IC50)
HPV
XLogP3-AA 5.7

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