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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
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- HCV Protease
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- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
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- Rabies virus (RABV)
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- West Nile virus
- Antiviral intermediates
L-Norleucine
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| Category | Influenza Virus |
| CAS | 327-57-1 |
| Description | L-Norleucine, an isomer of leucine, specifically affects skeletal muscle protein synthesis and has antiviral activity. |
Product Information
| Synonyms | Norleucine, L-; (S)-2-Aminohexanoic acid; (S)-Norleucine; (S)-α-Aminohexanoic acid; 2-Aminocaproic acid; L-(+)-Norleucine; L-2-Aminohexanoic acid; Caprine; Glycoleucine; Hexanoic acid, 2-amino-, (S)-; Norleucine; NSC 10378; NSC 74430; α-Aminocaproic acid |
| IUPAC Name | (2S)-2-aminohexanoic acid |
| Molecular Weight | 131.18 |
| Molecular Formula | C6H13NO2 |
| Canonical SMILES | CCCCC(C(=O)O)N |
| InChI | InChI=1S/C6H13NO2/c1-2-3-4-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1 |
| InChIKey | LRQKBLKVPFOOQJ-YFKPBYRVSA-N |
| Boiling Point | 234.0±23.0°C at 760 mmHg |
| Melting Point | >270°C (dec.) |
| Flash Point | 95.3±22.6 °C |
| Purity | ≥97% |
| Density | 1.038±0.1 g/cm3 |
| Solubility | Soluble in Aqueous Acid (Slightly), Water (Slightly) |
| Appearance | White to off-white crystalline powder |
| Application | A non-essential amino acid. Used as internal standard in amino acid analysis. |
| Storage | Store at RT |
| Complexity | 93.1 |
| Exact Mass | 131.094628657 |
| Index Of Refraction | 1.465 |
| In Vitro | L-Norleucine is an isomer of leucine, specifically affecting protein synthesis in skeletal muscle. L-Norleucine has antiviral activity. L-Norleucine interacts with hnRNPA2/B1 protein to suppresses the expressions of Twist1 and Snail, two inhibitors of E-cadherin, and promotes the expression of E-cadherin, resulting in the inhibition of tumor metastasis. |
| PSA | 63.32000 |
| Target | Influenza Virus; Endogenous Metabolite |
| Vapor Pressure | 0.0±1.0 mmHg at 25°C |
| XLogP3-AA | -1.5 |
